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Publicaciones 2013
Stasiłojć G, Pinto S, Wyszkowska R, Wejda M, Słomińska EM, Filipska M,Koszałka P, Swierczyński J, O'Connor JE, Bigda JJ. U937 variant cells as a model of apoptosis without cell disintegration. Cell Mol Biol Lett. Jun; 18(2):249-62. doi: 10.2478/s11658-013-0087-y. Epub 2013 Apr 20. PubMed PMID: 23605997.( 2013)
Estornell LH, Pons C, Martínez A, O'Connor JE, Orzaez D, Granell A. A VIN1GUS::GFP fusion reveals activated sucrose metabolism programming occurring ininterspersed cells during tomato fruit ripening. J Plant Physiol. 2013 Aug15; 170 (12):1113-21. doi: 10.1016/j.jplph.2013.03.007. Epub 2013 Apr 15. PubMedPMID: 23598179.( 2013)
Clothier R, Gómez-Lechón MJ, Kinsner-Ovaskainen A, Kopp-Schneider A, O'Connor JE, Prieto P, Stanzel S. Comparative analysis of eight cytotoxicity assays evaluated within the ACuteTox Project. Toxicol In Vitro. Jun; 27(4):1347-56. doi: 10.1016/j.tiv.2012.08.015. Epub 2012 Aug 23. PubMed PMID: 22951948.
Prieto P, Kinsner-Ovaskainen A, Stanzel S, Albella B, Artursson P, Campillo N, Cecchelli R, Cerrato L, Díaz L, Di Consiglio E, Guerra A, Gombau L, Herrera G,Honegger P, Landry C, O'Connor JE, Páez JA, Quintas G, Svensson R, Turco L,Zurich MG, Zurbano MJ, Kopp-Schneider A. The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox. Toxicol In Vitro. Jun;27(4):1357-76.doi:10.1016/j.tiv.2012.07.013. Epub 2012 Aug 16. PubMed PMID: 22922246. ( 2013)
Guzman C; Benet M; Moya M; Pisonero S; García-Mediavilla MV; Martínez-Chantar ML; González-Gallego J; Castell JV; Sánchez-Campos S; Jover R. The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARa; and repressed by C/EBPa: implications in FABP1 down-regulation in nonalcoholic fatty liver disease. BBA-Molecular and Cell Biology of Lipids. 1831: 803-818. (2013).
Carbajo-Pescador S, Ordoñez R, Benet M, Jover R, García-Palomo A, Mauriz JL, González-Gallego J. Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the antiangiogenic effect of melatonin in HepG2 liver cancer cells. British Journal of Cancer. 109: 83-91. (2013).
Rulcova A, Krausova L, Smutny T, Vrzal R, Dvorak Z, Jover R, Pavek P. Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α up-regulation in primary human hepatocytes. Pharmacological Reports. 65 (November – December). (2013).
Donato T, Jover R and Gómez-Lechón MJ. Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering. Current Drug Metabolism. (2013).
Codoñer-Franch, P; Tavárez-Alonso, S; Navarro-Ruiz, A; Laporta-Martín, P; Carratalá-Calvo,A; Alonso-Iglesias, E. “Biomarkers of inflammation in obese children: relationship with Vitamin D insufficiency”. Proceedings of the Nutrition Society, 72 (OCE1): E36. (2013)
Medina-Ramón A, Vallverdú-Queralt A, Arranz S, Ros E, Martínez-González MA, Sacanella E, Covas MI, Corella D, Salas-Salvadó J, Gómez-Gracia E, Ruiz-Gutiérrez V, Lapetra J, García-Valdueza M, Arós F, Saez GT, Serra-Majem L, Pinto X, Vinyoles E, Estruch R, Lamuela-Raventos RM. Gazpacho consumption is associated with lower blood pressure and reduced hypertension in a high cardiovascular risk cohort. Cross-sectional study of the PREDIMED trial. Nutr Metab Cardiovasc Dis. 2012 Nov 10. PMID:23149074
Barregard L, Møller P, Henriksen T, Mistry V, Koppen G, Rossner P Jr, Sram RJ, Weimann A, Poulsen HE, Nataf R, Andreoli R, Manini P, Marczylo T, Lam P, Evans MD, Kasai H, Kawai K, Li YS, Sakai K, Singh R, Teichert F, Farmer PB, Rozalski R, Gackowski D, Siomek A, Saez GT, Cerda C, Broberg K, Lindh C, Hossain MB, Haghdoost S, Hu CW, Chao MR, Wu KY, Orhan H, Senduran N, Smith RJ, Santella RM, Su Y, Cortez C, Yeh S, Olinski R, Loft S, Cooke MS. Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2'-deoxyguanosine. Antioxid Redox Signal. 2013 Jun 20;18(18):2377-91. doi: PMID: 23198723
Tresserra-Rimbau A, Medina-Remón A, Pérez-Jiménez J, Martínez-González MA, Covas MI, Corella D, Salas-Salvadó J, Gómez-Gracia E, Lapetra J, Arós F, Fiol M, Ros E, Serra-Majem L, Pintó X, Muñoz MA, Saez GT, Ruiz-Gutiérrez V, Warnberg J, Estruch R, Lamuela-Raventós RM. Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: The PREDIMED study. Nutr Metab Cardiovasc Dis. 2013 Jan 16. PMID: 23332727
Borrego S, Vazquez A, Dasí F, Cerdá C, Iradi A, Tormos C, Sánchez JM, Bagán L, Boix J, Zaragoza C, Camps J, Sáez G. Oxidative Stress and DNA Damage in Human Gastric Carcinoma: 8-Oxo-7'8-dihydro-2'-deoxyguanosine (8-oxo-dG) as a Possible Tumor Marker.
Int J Mol Sci. 2013 Feb 6;14(2):3467-86. PMID: 23389043
Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, Gómez-Gracia E, Ruiz-Gutiérrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA; PREDIMED Study Investigators. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013 Apr 4;368(14):1279-90. PMID:23432189
García-Heredia A, Kensicki E, Mohney RP, Rull A, Triguero I, Marsillach J, Tormos C, Mackness B, Mackness M, Shih DM, Pedro-Botet J, Joven J, Sáez G, Camps J. Paraoxonase-1 Deficiency Is Associated with Severe Liver Steatosis in Mice Fed a High-fat High-cholesterol Diet: A Metabolomic Approach
J Proteome Res. 2013 Mar 8. PMID:23448543
Pedro T, Martinez-Hervas S, Tormo C, García-García AB, Saez-Tormo G, Ascaso JF, Chaves FJ, Carmena R, Real JT. Oxidative stress and antioxidant enzyme values in lymphomonocytes after an oral unsaturated fat load test in familial hypercholesterolemic subjects. Transl Res. 2013 Jan;161(1):50-6. PMID: 23072926
Puchades MJ, Saez G, Muñoz MC, Gonzalez M, Torregrosa I, Juan I, Miguel A. Study of oxidative stress in patients with advanced renal disease and undergoing either hemodialysis or peritoneal dialysis Clin Nephrol. 2013 Jun 19. PMID:23782545
Leonardo De Tursi Ríspoli, Antonio Vázquez Tarragón, Antonio Vázquez Prado,Guillermo Sáez Tormo (CIBEROBN),Ali Mahmoud Ismail y Verónica Gumbau Puchol Estrés oxidativo; estudio comparativo entre un grupo de población normaly un grupo de población obesa mórbida
Bagan J, Sáez G, Tormos M, Hens E, Terol M, Bagan L, Diaz-Fernández J, Lluch A, Camps C. Interleukin-6 concentration changes in plasma and saliva in bisphosphonate-related osteonecrosis of the jaws. PMID: 23837828
Arós F, Corella D, Covas MI, Estruch R, Fiol M, Lapetra J, Gómez-Gracia E, Lamuela-Raventos RM, Martínez A, Martínez-González MA, Pintó X, Portillo MD, Ros E, Ruiz-Gutiérrez V, Saez G, Salas-Salvadó J, Serra-Majem L, Tur J. [HOW TO PUBLISH IN THE NEW ENGLAND JOURNAL OF MEDICINE AND NOT TO DIE WHILE TRYING IT; THE PREDIMED EXPERIENCE.] Nutr Hosp. 2013 Julio-Agosto;28(4):977-979. Spanish. No abstract available. PMID: 23889611
Rodeiro I, José Gómez-Lechón M, Perez G, Hernandez I, Herrera JA, Delgado R, Castell JV, Teresa Donato M. Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes. Phytother Res. 2013 May;27(5):745-52.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, et al. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol. 2013 Aug;87(8):1315-530.
Donato MT, Gómez-Lechón MJ. Fluorescence-based screening of cytochrome P450 activities in intact cells. Methods Mol Biol. 987:135-48 (2013).
Tolosa L, Gómez-Lechón MJ, Pérez-Cataldo G, Castell JV, Donato MT. HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved. Arch Toxicol. 87(6):1115-27 (2013)
Tolosa L, Rodeiro I, Donato MT, Herrera JA, Delgado R, Castell JV, Gómez-Lechón MJ. Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells. J Pharm Pharmacol. 2013 Jul;65(7):1073-82.