Photo | Name and surname | Address | + info | Biography |
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ARNAU LLOMBART, VICENTE Director/a Titulacio Master Oficial |
Despacho 2.3.32. ETSE. Avenida de la Universidad s/n. CP: 46100 Burjasot (Valencia). ------------------------------ I2SysBio. Parque Científico de la UV. Despacho B12. (9635) 43061 |
Biography | ||
[Biography, english version] |
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ARZALLUZ LUQUE, ANGELES |
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AYALA GALLEGO, GUILLERMO |
(9635) 43977 |
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BELTRAN SERRANO, VIOLETA |
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BRACHO LAPIEDRA, MARIA ALMA |
43018 |
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BUCETA FERNANDEZ, JAVIER |
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CALVO SAIZ, CONRADO JAVIER |
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CASAS YRURZUM, SERGIO |
(9635) 43557 |
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CUBUK -, CANKUT |
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DASI FERNANDEZ, FRANCISCO JOSE |
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DOMINGO CALAP, PILAR |
(9635) 43261 |
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DZUNKOVA -, MARIA |
Despacho 3.2.2 I2SysBio - Instituto de Biología Integrativa de Sistemas Parque Científico de la Universidad de Valencia C/ Catedràtic Agustín Escardino, 9 46980 Paterna (València) 43649 |
Biography | ||
Mária Džunková got her first experience with the high throughput DNA sequencing at the Czech Academy of Sciences at the time when she studied at the University of Life Sciences in Prague (2005-2010). Then she moved to Spain for her PhD studies at the University of Valencia (2010-2016) which included a research stay at the Harvard University (2014). After defending her PhD thesis entitled ”Metagenomics of the Human Gut Microbiome Directed by the Flow Cytometry” she got a postdoc position at the Australian Centre for Ecogenomics at the University of Queensland (2016-2019), where she developed “single-cell viral tagging” method for exploring the phage host range without the need for microbial culturing and applied it to the human gut microbiome. She was invited to a second postdoc (2016-2021) at the DOE Joint Genome Institute (Lawrence Berkeley National Laboratory) to continue with her microbial single-cell genomics techniques. In California she studied the relationships between the phages and bacteria in environmental samples and explored new targeted single-cell genomics techniques for discovering symbiotic microbes of the marine soft-bodied animals capable of producing bioactive molecules. She joined the Institute for Integrative Systems Biology (I2SysBio) in December 2021 to set up her Microbial Single-Cell Genomics research group. |
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FERRIS CASTELL, RICARDO Coordinador/a Curs |
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GAGO BADENAS, FEDERICO |
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GALAN ALBIÑANA, AMPARO |
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GIL GARCIA, ROSARIO Coordinador/a de Programa de Doctorat |
Grup de Genètica Evolutiva, despatx 3.2.3 Institut de Biologia Integrativa de Sistemes (I2SysBio), Parc Científic de la Universitat de València, edifici 4 C/ Catedràtic Agustín Escardino, 9 46980 Paterna (València) (9635) 43824 |
Biography | ||
PhD in Pharmacy from the Universitat de València (1991), I did a postdoctoral stay of more than 3 years at the Eccles Institute of Human Genetics (University of Utah, USA). After 15 years dedicated to the study of the yeast Saccharomyces cerevisiae from almost any point of view (study of the cell wall, model system for the study of human tumor suppressor genes, analysis of stress and contamination in brewing yeast or global gene expression in wine yeasts), I joined the field of bacterial genomic evolution, in which I have been working since 2001 as a member of the Evolutionary Genetics group of the Universitat de València, where I am currently Full Professor of Genetics. I do my research at the Institute for Integrative Systems Biology (I2SysBio), a joint collaborative center Universitat de València - CSIC. Since 2001, my work has been mainly devoted to the study of the genome of endosymbiotic bacteria, which live inside specialized cells of insect with restricted diets (such as aphids, weevils or mealybugs), to understand the relationship between these bacteria and their hosts, the bacterial genome reduction in these conditions, and its consequences for the inferred metabolic network. As a complement to these studies, I have also been involved in studies on the definition of the minimal genome, essential for the maintenance of a living cell, and its implications in the field of Synthetic Biology. In recent years, our consolidated model system to study symbiotic interactions is the German cockroach Blattella germanica. Cockroaches are specially interesting because two symbiotic systems coexist in each individual, an obligate endosymbiont and a complex gut microbiota. We have developed strategies to better understand the implication of each sytem in the host welfare, and their putative crosstalk. More recently, we are focusing on the host mechanisms to control the symbionts, with special interest in antimicrobial peptides and microRNAs. - Host-symbiont communication and its utility in biological pest and pathogen control (SYMB-CONTROL, PID2021-128201NB-I00; co-financed MICIN-UEFEDER-AEI, EU and Spain)
Recent and selected publications Cazzaniga, M., R. Domínguez-Santos, J. Marín-Miret, R. Gil, A. Latorre, C. García-Ferris (2023). Exploring gut microbial dynamics and symbiotic interaction in Blattella germanica using rifampicin. Biology 12:955. doi: 10.3390/biology12070955 Latorre, A., R. Domínguez-Santos, C. García-Ferris, R. Gil (2022). Of cockroaches and symbionts: recent advances in the characterization of the relationship between Blattella germanica and its dual symbiotic system. Live 12: 290. doi: 10.3390/life12020290 Garzón, M.J., M. Reyes-Prieto, R Gil (2022). The minimal translation machinery: what we can learn from naturally and experimentally reduced genomes. Front. Microbiol. 13:858983. doi: 10.3389/fmicb.2022.858983 Solana, J., E. Garrote-Sánchez, R. Gil (2021). DELEAT: gene essentiality prediction and deletion design for bacterial genome reduction. BMC Bioinformatics 22:444. doi: 10.1186/s12859-021-04348-5 Domínguez-Santos R, A.E. Pérez-Cobas, P. Cuti, V. Pérez-Brocal, C. García-Ferris, A. Moya, A. Latorre, R. Gil (2021). Interkingdom gut microbiome and resistome of the cockroach Blattella germanica. mSystems 6:e01213-20. doi: 10.1128/mSystems.01213-20 Reyes-Prieto, M., R. Gil, M. Llabrés, P. Palmer-Rodríguez, A. Moya (2021). The metabolic building blocks of a minimal cell. Biology, 10:5. doi: 10.3390/biology10010005 Gil, R., A. Latorre (2019). Unity makes strength: a review on mutualistic symbiosis in representative insect clades. Life 9: 21; doi:10.3390/life9010021. Gil, R., C. Vargas-Chavez, S. López-Madrigal, D. Santos-García, A. Latorre, A. Moya (2018). Tremblaya phenacola PPER: An evolutionary beta-gammaproteobacterium collage. ISME J. 12:124-135. doi: 10.1038/ismej.2017.144 López-Madrigal, S., R. Gil (2017). Et tu, Brute? Not even intracellular mutualistic symbionts escape horizontal gene transfer. Genes 8:247. doi: 10.3390/genes8100247 Lloréns-Rico, V., J. Cano, T. Kamminga, R. Gil, A. Latorre, W. H. Chen, P. Bork, J. I. Glass, L. Serrano, M. Lluch-Senar (2016). Bacterial antisense RNAs are mainly the product of transcriptional noise. Sci. Adv. 2:e1501363. doi: 10.1126/sciadv.1501363 Klein, A., L. Schrader, R. Gil, A. Manzano-Marín, L. Flórez, D. Wheeler, J. H. Werren, A. Latorre, J. Heinze, M. Kaltenpoth, A. Moya, J. Oettler (2016). A novel intracellular mutualistic bacterium in the invasive ant Cardiocondyla obscurior. ISME J. 10:376-388. doi: 10.1038/ismej.2015.119 Gil, R., J. Peretó (2015). Small genomes and the difficulty to define minimal translation and metabolic machineries. Front. Ecol. Evol. 3:123. doi: 10.3389/fevo.2015.00123 López-Madrigal, S., A. Latorre, A. Moya, R. Gil (2015). The link between independent acquisition of intracellular gamma-endosymbionts and concerted evolution in Tremblaya princeps. Front. Microbiol. 6:642. doi: 10.3389/fmicb.2015.00642 Gil, R. (2014). The minimal gene-set machinery. In Encyclopedia of Molecular Cell Biology and Molecular Medicine: Synthetic Biology, 2nd edition. Meyers RA (ed.). Wiley-VCH Verlag GmbH & Co. pp. 1-36. doi: 10.1002/3527600906.mcb.20130079 López-Madrigal, S., A. Beltrà, S. Resurrección, A. Soto, A. Latorre, A. Moya, R. Gil (2014). Molecular evidence for ongoing complementarity and horizontal gene transfer in endosymbiotic systems of mealybugs. Front. Microbiol. 5:449. doi: 10.3389/fmicb.2014.00449 Oakeson, K. F.*, R. Gil*, A. L. Clayton, D. M. Dunn, A. C. von Niederhausern, C. Hamil, A. Aoyagi, B. Duval, A. Baca, F.J. Silva, A. Vallier, D. G. Jackson, A. Latorre, R. B. Weiss, A. Heddi, A. Moya, C. Dale (2014). Genome degeneration and adaptation in a nascent stage of symbiosis. Genome Biol. Evol. 6:76-93. doi: 10.1093/gbe/evt210 *Equal contribution. López-Madrigal, S., A. Latorre, M. Porcar, A. Moya, R. Gil (2013). Mealybugs nested endosymbiosis: going into the ‘matryoshka’system in Planococcus citri in depth. BMC Microbiol. 13:74. doi: 10.1186/1471-2180-13-74 Moya, A., R. Gil, A. Latorre., J. Peretó, M.P. Garcillán-Barcia, F. de la Cruz (2009). Towards minimal bacterial cells: evolution versus design. FEMS Microbiol. Rev. 33:225-235. doi: 10.1111/j.1574-6976.2008.00151.x Moya, A., J. Peretó, R. Gil, A. Latorre (2008). Learning how to live together: genomic insights into prokaryote-animal symbioses. Nature Rev. Genet. 9:218-229. doi:10.1038/nrg2319 Tamames, J.*, R. Gil*, A. Latorre, J. Peretó, F.J. Silva, A. Moya (2006). The frontier between cell and organelle: genome analysis of Candidatus Carsonella ruddii. BMC Ecol. Evol. 7:181. doi: 10.1186/1471-2148-7-181 *Equal contribution. T. Gabaldón, J. Peretó, F. Montero, R. Gil, A. Latorre, A. Moya (2007). Structural analyses of a hypothetical minimal metabolism. Phil. Trans. R. Soc. B. Biol. Sci. 362:1751-1762. doi: 10.1098/rstb.2007.2067 Pérez-Brocal, V., R. Gil, S. Ramos, A. Lamelas, M. Postigo, J. M. Michelena, F. J. Silva, A. Moya, A. Latorre (2006). A small microbial genome: the end of a long symbiotic relationship? Science 314:312-313. doi: 10.1126/science.1130441 Gil, R., F. J. Silva, J. Peretó, A. Moya (2004). Determination of the core of the minimal bacterial gene set. Microbiol. Mol. Biol. Rev. 68: 518-537. doi: 10.1128/MMBR.68.3.518-537.2004 Gil, R., B. Sabater-Muñoz, A. Latorre, F. J. Silva, A. Moya (2002). Extreme genome reduction in Buchnera spp.: towards the minimal genome needed for symbiotic life. Proc. Natl. Acad. Sci. USA 99: 4454-4458. doi: 10.1073/pnas.062067299 |
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GOMEZ CABAÑES, BORJA |
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GOMEZ MARTINEZ, HELENA |
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GONZALEZ CABRERA, JOEL Delegat/Delegada Rector/A Per a Accions Estrategiques d'Investigacio |
(9635) 43122 |
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GONZALEZ CANDELAS, FERNANDO |
Despacho 2.6.I Instituto de Biología Integrativa de Sistemas, I2SysBio (CSIC-UV). Parc Científic. Paterna. (9635) 43653 |
Biography | ||
Fernando Gonzalez Candelas, PhD (University of Valencia, 1987) is Professor of Genetics at the University of Valencia since 2006 and head of the “Evolution and Health” Research Unit at the Institute for Integrative Systems Biology UV-CSIC (I2SysBio) at the same university. In addition, he has a joint appointment at the FISABIO-Public Health through the joint research unit “Infection and Public Health” with the University of Valencia and at the CIBERESP (Centre for Networked Research on Biomedicine – Public Health and Epidemiology). |
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GORDILLO GONZALEZ, FERNANDO |
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GRILLO RISCO, RUBEN |
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LLORENS RICO, VERONICA |
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LOPEZ -, MARIANA |
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LOZANO IBAÑEZ, MIGUEL |
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MALMIERCA MERLO, PABLO MANUEL |
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MARIN NAVARRO, JULIA VICTORIA |
(9635) 43014 |
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MINGUEZ PANIAGUA, PABLO ALBERTO |
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MONZO CATALUÑA, CAROLINA |
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MORENO TRIGOS, YOLANDA |
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MOYA SIMARRO, ANDRES |
Integrative Systems Biology Institute (I2Sysbio); University of València and Spanish Research Council (CSIC); c/ Catedrático José Beltrán 2, 46980 Paterna, València, Spain. Foundation for the Promotion of Sanitary and Biomedical Research of Valencian Community (FISABIO); Avenida de Cataluña 21, 42... (9635) 43480 |
Biography | ||
He studied Biology and Philosophy simultaneously at the University of Valencia, obtaining his Ph.D. in Biology in 1983 and Philosophy (Extraordinary Award) in 1988. He did his postdoctoral stay in 1985-1986 with a Fulbright grant at the University of California at Davis (USA). He had been visiting professor at the University of California at Irvine (USA) in 1988 and 1994, and in 2019 professor on a sabbatical stay with a Fulbright grant at Harvard University. In 1986 he created the Evolutionary Genetics group in the Dept. of Genetics at the University of Valencia, where he has been a professor since 1993. He was the director of this Dept. from 1995 to 1998. He has been the promoter of the Cavanilles Institute of Biodiversity and Evolutionary Biology of the University of Valencia and its director from its creation in 1998 until 2010. He has also been a promoter of the Astrobiology Center (INTA-CSIC) and the Centro Superior de Investigación en Salud Pública de la Conselleria de Sanidad del Gobierno Valenciano (CSISP), of which he was its director in 2012. The CSISP was integrated into the Valencian Foundation for Promoting Health and Biomedical Research of the Valencian Community, FISABIO. He was the FISABIO-Public Health division's scientific director from 2013 until July 2014. Since August 2014, he has directed, within FISABIO, the FISABIO Chair for the Promotion of Biomedical Research, an Institutional Chair of the University of Valencia. He is the author of about 600 publications, including scientific articles, reviews, book chapters, and books on Genetics, Evolution, and Philosophy (20,700 citations, h-index of 74). He has participated in several patents and created a spin-off company. Experimental evolution of viruses and genomics and metagenomics of bacteria and microbial communities represent the research areas where he has made the most significant scientific contributions. He introduced Genomics in Spain, and his group sequenced the first genome of a bacterium, entirely carried out in Spain. He has done extensive work in disseminating and reflecting on science and has published several books on evolutionary theory and the scope of evolutionary thought. He currently focuses his research on symbiosis, mainly studying the human microbiome and other organisms from an evolutionary, systems biology, and synthetic biology perspective. He has supervised 35 doctoral theses, and many national and foreign scientists have been trained in his research group. He has received competitive funding from regional, national, European, and international agencies and has been the principal investigator of national, European, and international projects. He has given lectures and courses in European countries, Latin America, the United States, and Asia. He has formed or is a member of commissions of research evaluation agencies in Spain and its autonomous communities, different European and Latin American countries, and the European Union. He is a member of several scientific societies, founder of the European Society of Evolutionary Biology, the Spanish Society of Virology, and the Spanish Society of Evolutionary Biology, of which he has been its president. He is editor-in-chief, associate editor, or editorial board member of several scientific and philosophical journals. He has received the following distinctions: the City of Barcelona Award for Scientific Research (1996), "Fellow" of the "American Association for the Advance of Science" (1998), the Diario Médico Award (2006), Diploma of the President of the Valencian Government for Excellence in Biomedical Research (2010), National Genetics Award (2012), Lilly Award in Preclinical Biomedical Research (2013), Mexico Award for Science and Technology (2015), Dr. Honoris Causa by the Menéndez Pelayo International University (2016), Advisor to the Gadea Foundation (2017), Maestro Andrés Laguna Award (2019), Alberto Sols Award for Research in Health Sciences (2022). |
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NAVARRO CERDAN, JOSE RAMON |
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NOGALES ENRIQUE, JUAN |
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OTERO MURAS, IRENE |
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PALERO PASTOR, FERRAN |
-- Ferran ***************************************************** PALERO Ferran, Ph.D. M.Sc. Institut Cavanilles de Biodiversitat i Biologia Evolutiva (ICBIBE) Carrer del Catedrátic José Beltrán Martinez, 2 46980 Paterna, Valencia E-mail: Ferran.Palero@uv.es Tel: 0034963543787 // Associ... (9635) 43787 677679429 |
Biography | ||
Ferran Palero holds a PhD in Biology (University of Barcelona, 2008) and an MSc in Mathematical Research (UPV, 2009). He has completed postdoctoral research in Austria (Institute of Science and Technology, 2009-2011), France (National Institute of Agronomic Research, 2012-2014), Blanes (Center for Advanced Studies of Blanes, 2014-2016) and Poland (University of Lodz, 2017-2019). He is currently developing his BIOPACKS research project as a "CIDEGENT" Researcher at the Cavanilles Institute of Biodiversity and Evolutionary Biology (ICBIBE, University of Valencia). The BIOPACKS project (BIOdiversity Patterns of Crustacea from Karstic Systems) focuses on the study of groundwater aquatic fauna incorporating new molecular methods in order to discover molecular adaptations and new enzymes with potential biotechnological application. |
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PANADERO ROMERO, JOAQUIN JAVIER |
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PASCUAL MORA, MARIA |
(9616) 25635 |
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PAZOS CABALEIRO, FLORENCIO |
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PERETO MAGRANER, JULI |
Institut de Biologia Integrativa de Sistemes (I2SysBio, UV-CSIC) C. José Beltrán 2 46980 Paterna (9635) 43666 |
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PICO MARCO, JESUS |
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PONCE DE LEON CAPURRO, MIGUEL |
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ROMERA GINER, SERGIO |
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RUIZ GARCIA-TREVIJANO, ELENA |
(9639) 83886 |
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SALGADO BENITO, JESUS |
Instituto de Ciencia Molecular Despacho 2.10 / Lab. 2.8 Edificio de Institutos de Paterna Polígono La Coma s/n 46980 Paterna (Valencia) (9635) 43016 |
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SANCHEZ DEL PINO, MANUEL MATEO |
(9635) 43464 |
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SEBASTIAN LEON, PATRICIA |
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SOLER SAEZ, IRENE |
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SUKHOTSKA -, IRINA |
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TARAZONA CAMPOS, SONIA |
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VALVERDE CASTILLO, SERGIO |