Department of biochemistry and molecular biology

Professor Eulalia Alonso:

1. Metabolism of arginine in animal models of metabolic pathology.
2. Metabolism of arginine in diabetic patients.
3. Biochemistry of polyamines.

Professor José Vicente Castell Ripoll:

1. Molecular mechanisms of hepatotoxicity due to drugs.
2. Mechanisms of inmune hipersensitivity reactions to drugs.

Professor María Teresa Donato Martín:

1. Molecular mechanisms of hepatotoxicity due to drugs.
2. Mechanisms of inmune hipersensitivity reactions to drugs.

Professor Micaela Gómez García & Amelia Murgui Faubel:

1. Molecular basis of pathogenicity of yeasts/pathogen fungi.
2. Molecular diagnosis and therapeutic targets of fungi.
3. New strategies for the development of active inmunization in the prevention of systematic infections by candida albicans using murine models

Professor Pilar López García:

1. Metabolism of Xenobiotics.
2. Oxidative stress and post-translational modulation of hepatic CYP.
3. Molecular basis of drug-induced autoimmune hepatitis. In vitro models and functional characterisation of biotransformation enzymes.

Professor Ramiro Jover Atienza:

1. Development of hepatic and non-hepatic cell models with capacity of biotransformation of xenobiotics.
2. Control of the hepatic gene expression during physiopathological processes.

Professor José Enrique O'Connor Blasco:

1. Study of metabolical mechanisms in cytotoxicity and cell death.
2. Development of flow cytometry tests for the detection and quantification of toxicity.
3. Development of functional applications for flow cytometry in Immunology.

Professor Guillermo Sáez Tormo:

1. Cytotoxic action mechanism of free radicals on biological systems.
2. Role of oxidative stress in experimental and human carcinogenesis.
3. Expression of proto-oncogenes and tumor-suppresing genes in human carcinogenesis.
4. Oxidative stress and gene expression in experimental and human carcinogenesis.
5. Oxidative stress as physiopathological mechanism of heart diseases.

Professor Juan Saus Mas:

1. Role of GPBP kinase protein in en Goodpasture's Syndrome (GS).
2. Role of GPBP kinase protein in IgA nephropathy.
3. Role of GPBP kinase protein in cancer and degenerative diseases.

Professors Juan Viña Ribes and Luis Torres Asensi:

1. Metabolism of amino acids and vitamin A.
2. Biochemistry of Transporters.
3. Studies of gene expression in situations of physiopathological relevance.