Study of the novel molecular, biochemical, cellular and genetic mechanisms  involved in the systemic effects of chronic obstructive pulmonary disease (COPD). 

Study of the vascular inflammation induced by different risk factors of atherosclerosis: angiotensin-II, menopause, cigarette smoke, metabolic syndrome, insulin resistance, primary hypercholesterolemia or obesity.

Study of the role of nuclear receptors in inflammation and angiogenesis and their involvement in abdominal aortic aneurism, obesity and atherosclerosis . 

Development of new drugs for the treatment of cardiometabolic disorders.