BioCalibra is an automated calibration device developed by CALAGUA that allows quantifying the kinetic and stoichiometric parameters of the WWTP simulation models most accepted by the scientific community. BioCalibra allows to perform in a highly automated way, the tests necessary for the calibration of the parameters of greater influence of the activated sludge models. In addition, it allows to carry out a great diversity of experiments designed to evaluate the biological process, such as: determination of the biodegradability of the wastewater, verification of the existence of toxic compounds and determination of possible interferences or potential impacts on the treatment processes. BioCalibra allows to optimize the calibration process, reducing both the analysis time, as well as, the human and technical resources required for its application.