Description
Brain cell senescence remains unexplored as a target for neuroprotection in stroke. The aim is to characterise brain cell senescence associated with ageing and stroke in a rat model, and to reposition a senolytic drug, Navitoclax, as an effective neuroprotectant for use as an adjunct to endovascular treatment in ischaemic stroke. The influence of gender will also be analysed.
Keywords
Ischaemic stroke, cellular senescence, neuroprotection
Manager UV
- Salom Sanvalero, Juan Bautista
- PDI-Associat/Da Universitari/A
Frascati classification
