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Characterising cellular mechanisms of antiretroviral-induced toxicity

Description

We study the mechanisms responsible for the toxicity of antiretroviral therapy in different organs and tissues, with special emphasis on three of the main adverse effects associated with this treatment: liver toxicity, metabolic alterations and neurotoxicity.

Keywords

hepatotoxicity, antiretrovirals, mitochondria, HIV, neurotoxicity, bioenergetics

Frascati classification