Experimental models in mitochondrial neurodegenerative diseases
Obtaining experimental models and characterisation of the effects produced by:
- Systemic and tissue-specific loss/gain of frataxin and paraplegia function in Drosophila.
- Functional alterations of both proteins in humanised paraplegia and frataxin models in Drosophila.
Genetics of Schizophrenia
Study of gene expression, identification of biomarkers of treatment response in schizophrenia, and characterisation of the cell response to the drug in models derived from Induced Pluripotent Stem Cells (iPSCs).
