Biomedical applications of bacteriophages, including diagnosis, prevention, and therapy, as an alternative tool against multidrug-resistant bacteria. Isolation and characterization of novel phages, directed evolution for phage optimization, resistant emergence, and nanotechnology.
We use viruses as model organisms in the laboratory to study evolutionary processes on an experimental basis.
- To delve into the molecular mechanisms that control the interaction of insects with their viral and bacterial pathogens.
- To develop strategies that enhance the use of bioinsecticides by modifying the immune response to pathogen attack.
This line of research focuses on the study of the epidemiology of rotavirus and norovirus through the application of molecular techniques (RT-PCR, qPCR, cDNA sequencing, etc.) and the detection of new variants of viral genotypes.
The aim of this line of research is to study the pathogenic mechanisms and the immune response of infections by the two main enteric viruses (rotavirus and norovirus).
The aim of this line of research is to study the interactions that occur between enteric viruses and the host without excluding the interactions that occur between enteric viruses and the intestinal microbiota or the interaction between the intestinal microbiota and the host.
Monitoring natural and anthropogenic environments for disease surveillance, specially viral outbreaks. Detection of emerging viruses in natural environments and development of quantification techniques for population monitoring. Study of new transmission routes of emerging viruses.
Using various experimental approaches, we aim to identify and characterise mechanisms in the generation of RNA virus diversity, and to obtain quantitative estimates of mutation rates in RNA viruses.
