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Animal models of Friedreich’s Ataxia and Spastic Paraplegia Type 7

Type: Biological material
Description

Different Drosophila lines for the study of Friedreich’s Ataxia and Spastic Paraplegia Type 7:

  • With generalised and tissue-specific reduction/increase of the expression of the endogenous gene that encodes frataxin and paraplegin respectively.
  • With expression of the human genes.
  • With expression of the human mutation responsible for both diseases.