Website: http://www.haptens-antibodies.com/
| Members | Category | Contact |
|---|---|---|
| Antonio Abad Somovilla | Emeritus Professor (Director) | 963544509 antonio.abad@uv.es |
| Ismael Navarro Fuertes | Assistant Doctor Professor | 963543886 ismael.navarro-fuertes@uv.es |
| Daniel Suay Fuertes | PIND (Doctoral Student) | |
| Daniel López Puertollano | Margarita Salas Doctor | daniel.lopez@uv.es |
| Vicente Folgado García | PIND | vicente.folgado@uv.es |
| Víctor García García | PIND (Doctoral Student) | victor.garcia-garcia@uv.es |
| Diego Alonso Ulloa Campos | Doctoral Student | dieuam@alumni.uv.es |
| Anna Romero Ventura | Doctoral Student FPI | anroven@alumni.uv.es |
| Arev Sarqsyan | Doctoral Student FPI | asarg@alumni.uv.es |
PROOF OF CONCEPT’ PROJECTS 2022. Ref. PDC2022-133559-C21
Project/AEI/10.13039/501100011033/European Union NextGenerationEU/PRTR
Valorisation of immunoreagents for the control of the mycotoxins zearalenone and alternariol by fast methods. Haptenes and bioconjugates
The research group of the Department of Organic Chemistry ‘Synthesis of Molecules for Biotechnological Applications’ (SYMOBIA), led by Professors Antonio Abad Somovilla and Ismael Navarro Fuertes, is participating in the development of a project corresponding to the 2022 call for ‘Proof of Concept’ projects, financed with European funds from the Recovery, Transformation and Resilience Plan (NextGenerationEU) within the State Programme to promote scientific and technical research and its transfer, of the state plan for scientific and technical research and innovation 2021-2023.
Objective
The exposure of consumers to mycotoxins via food is an issue of major social concern that also entails significant economic costs to the agri-food industry. Consequently, governmental agencies have issued maximum levels for the main mycotoxins that may be present in food and feed. For this group of contaminants, antibody-based methods are used as detection techniques in laboratories around the world. In fact, many immunodiagnostic companies in the agri-food sector market kits for the control and detection of mycotoxins.
Within the coordinated project RTI2018-096121 that supports this proposal, our research groups succeeded in synthesising two innovative haptens for the mycotoxins zearalenone and alternarion and in generating antibodies with high affinity and specificity towards them. These immunoreagents have already been implemented on a laboratory scale in immunoanalytical systems similar to those used by the food diagnostics industry, and have proven to be able to robustly determine alternaril and zearalenone at concentrations below those specified in international standards. Consequently, the immunoreagents developed under the RTI2018 project have enormous potential to attract the interest of companies offering solutions to a global problem that severely affects consumer health and livestock welfare. The aim of this project is to increase their transfer potential.
Duration: 01/12/2022 to 30/11/2024.
Total project budget: 61,985 €
