Research projects funded by the Interministerial Commission on Science and Technology (CICYT)
SAF2013-43441-P
Modulación de la autofagia epitelial por los macrófagos: relevancia en la reparación mucosa en la enfermedad inflamatoria intestinal (2014, 3 years)
IP: Mª Dolores Barrachina Sancho and Francisca Sara Calatayud Romero
SAF2010-2023
Pathophysiological importance of theHIF-induced geneexpressionininflammatory bowel disease(2011,3 years).
IP: M. Dolores Barrachina
SAF2010-16030
Study of thecellular and molecular mechanismsthat mediatevasculartoxicityinducedby antiretroviral therapy(2011,3 years)
IP: Ángeles Álvarez
SAF2007-64201
Studyof theCellular and MolecularMechanismsThatMediatevasculartoxicityinducedbyantiretroviraltherapy(2011, 3 years)
IP: M. Dolores Barrachina.
SAF2007-60021
Efectos de los fármacos antirretrovirales sobre la interacción leucocito-endotelio. (2007, 3 years)
IP: Ángeles Álvarez.
SAF2005-01366
Effectsof antiretroviral drugsonleukocyte-endotheliuminteraction.(2007,3 years)
IP: Juan V. Esplugues.
SAF2004-06211
Pathophysiologicalrelevanceofinduciblenitric oxide synthaseinthe developmentofgastric lesionsinduced byNSAIDs(2004,3 years)
IP: M. Dolores Barrachina.
SAF2004-002600
Nitric oxideas a regulatorof gene expressionviainducibletranscriptionfactorhypoxia (HIF): molecular mechanismsand physiologicaland pathological implications(2004,1 year)
IP: Juan V. Esplugues.
SAF2001-0763
Actionsof nitric oxide oncell respirationand their involvement intheirpathogenic effects(2001,3 years)
IP: Juan V. Esplugues.
SAF 99-0114
Neurohormonalregulationofgastric function:role of nitric oxide(1999,3 years)
IP: M. Dolores Barrachina.
SAF98-0118
Roleof nitric oxide inthegastrointestinalresponseto stress:involvementpathophysiological andpharmacologicalbases of action(1998,3 years)
IP: Juan V. Esplugues.
IFD97-1029
Programme (ERDF)gastroprotectionbynitroglycerin patch.(1997,3 years)
IP: Juan V. Esplugues
DGICYT PM95-0145
Increased gastric mucosal defense induced by endotoxin and other stressors: Characterization of the role of nitric oxide. (1995, 3 years)
IP: Juan V. Esplugues
SAF95-0472
Pharmacologicalanalysisofthegastrointestinalactionsnitrovasodilators.(1995,3 years)
IP: Juan V. Esplugues.
Research projectsfunded by theHealth Research Fund
PI14/00312
Papel de los fármacos anti-VIH en la aparición y/o progresión de la enfermedad de higado graso no alcohólico. (2015, 3 years)
IP: Juan V. Esplugues Mota y Nadezda Apostolova
PI13/01025
Disfunción endotelial-mitocondrial, estrés de retículo y autofagia en la diabetes tipo 2: Implicaciones fisiopatológicas, clínicas y terapeúticas (2014, 3 years).
IP: Victor Manuel Víctor González
PI13/00073
Efecto de la pérdida de peso sobre marcadores de estrés de retículo endoplasmático en la obesidad mórbida: Implicaciones fisiopatológicas y nuevas dianas terapéuticas (2014, 3 years).
IP: Milagros Rocha Barajas
PI11/00327
Characterization of novelcellular mechanisms ofantiretroviralhepatotoxicity.
IP: Juan V. Esplugues Mota
CB06/04/0071
Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas - CIBERehd (2006-present)
IP: Juan V. Esplugues.
FIS PI10/01195.
Biomedical Research CentreNetwork inthe subject areaofLiver and DigestiveDiseases-CIBERehd(2006-present).
IP: Víctor M. Víctor.
FIS PI081325
Toxicidad mitocondrial por fármacos antirretrovirales: Caracterización de un nuevo mecanismo agudo de acción (2008, 3 years)
IP: Juan V. Esplugues
HelpIII(2009-1010)within theProgramofSupport forYoung ResearchersSupportCIBERehdyoung memberof theCIBERpartnerforhiring aresearch technician(2008).
IP: Ángeles Álvarez.
FIS PI07/00171.
Oxidative stress andendothelial dysfunction: role ofnitricoxide(2008,2 years).
IP: Victor M Victor.
ISupport(2007-2008)ayoung memberof theCIBERpartner.Helpayoung memberof theCIBERpartnerforhiring aresearch technician(2007).
IP: M. Dolores Barrachina
C03/02
HelpsDevelopmentCooperative ResearchThematic Networks.RNIHG.National Networkfor Research inHepatology andGastroenterology(2003,3 years)
IP: Adolfo Benages M. Dolores Barrachina, Sara Calatayud.
CP03/0024
Role of nitric oxidein cellular respirationinnormoxiaand hypoxia:physiological andpathophysiologicalimplications(2004,3 years).
IP: Víctor M. Víctor.
FISPI02/0461
Effectsof leptin onleukocyte-endotheliuminteractions(2002,3 years).
IP: Sara Calatayud.
FIS 01/1187
Mechanismsofnitric oxide signalingin thegastrointestinalfunctionalism: Involvementof the nervous andimmunecomponents(2001,3 years).
IP: Mª Dolores Barrachina.
FIS 88-1947
Influenceof blood pressurein the genesis ofgastric damageinducedPafacetherand thromboxane A2Duration: 1 year
FIS 87-1375
Study ofgastricactionblockersofcalcium channels.Duration: 1 year
Research projects fundedby the Generalitat Valenciana
PROMETEOII/2014/035
Farmacología del tracto digestivo y la inflamación. Programa de ayudas para el desarrollo de actuaciones de I+D por grupos de investigación de excelencia Fase II (2014, 4 años)
IP: Juan V. Esplugues Mota
ACOMP/2013/236
Ayuda complementaria para el proyecto "Caracterización de nuevos mecanismos celulares de heptoxicidad por antirretrovirales" (2013, 1 año)
IP: Juan V. Esplugues Mota
PROMETEO/2010/60
PrometheusProgramforexcellent researchgroups(2010,5 years)
IP: Juan V. Esplugues.
ACOMP/2010/169
Additional aidfor R& Dbythe ValencianRegional Ministryon Education(2010, 1year)
IP: Víctor M. Víctor
ACOMP/2010/207
Additional aidtoprojectantiretroviralmitochondrialtoxicity:characterization of a novelacutemechanismof action.(2010, 1year)
IP: Juan V. Esplugues.
ACOMP/2009/194
Additional aidtoprojectantiretroviralmitochondrialtoxicity:characterization of a novelacutemechanismof action.(2009, 1year)
IP: Juan V. Esplugues.
AP-030/09
Study ofcardiovascularadverse effectsinducedby antiretroviral therapy(2009, 1year)
IP: Ángeles Álvarez.
ACOMP/2009/009
Additional aidfor R& Dbythe ValencianRegional Ministryon Education(2009, 1year)
IP: Víctor M. Víctor.
GVPRE/2008/216
Effectof statins onthetranscriptionfactorHIF-1andendothelininhuman endothelialcellssubjected tohypoxia(2008,1 year)IP: M. Ángeles Martínez.
GV/2007/074
Systematic studyof the effectof antiretroviral drugsonleukocyte-endotheliuminteractions(2007, 1year)
IP: Ángeles Álvarez.
GV2006-341
Nitroglycerinand nitric oxide:mechanismsof action onmitochondriaand oxidative stress(2006, 1year)
IP: Víctor M. Víctor.
ACOMP/2007/079
Ayuda complementaria al proyecto al proyecto Protección mucosa gastrointestinal: una aproximación integradora desde el óxido nítrico mitocondria y HIF (2007, 1 año)
IP: Juan V. Esplugues.
ACOMP/2006-246
Additional aidto the projectthe projectProtectiongastrointestinalmucosa:an integrative approachfrommitochondrialnitric oxideandHIF(2007, 1year)
IP: Juan V. Esplugues.
GVAE06-137
Vasculartoxicityof drugs usedin the therapyof AIDS(2006, 1year)
IP: Juan V. Esplugues.
GRUPOS 05/043
ResearchSupportgroups(2005, 1year)
IP: Juan V. Esplugues.
GV2004-A-147
Effectof nitric oxide oncell respirationandphysiologicaland pathophysiologicalimplications.(2004, 1year)
IP: Víctor M. Víctor
ACOMP07-297
Additional aidtoprojectpathophysiological importance of theinduciblenitric oxidesynthaseingastric lesionsinduced byNSAIDs(2007, 1year)
IP: M. Dolores Barrachina.
ACOMP06/237
Additional aidtoprojectpathophysiological importance of theinduciblenitric oxidesynthaseingastric lesionsinduced byNSAIDs(2006, 1year)
IP: M. Dolores Barrachina.
GV04B-185
Pathophysiologicalrelevanceofinduciblenitric oxide synthaseinthe developmentofgastric lesionsinduced byNSAIDs(2004,2 years)
IP: M. Dolores Barrachina.
GV04-B-184
Actionsof nitric oxide oncell respirationand their involvement intheirpathogenic effects(2004,2 years). .
IP: Juan V. Esplugues
S03/226
ProjectExcellenceValencian Agencyfor Scienceand Technology(2003,2 years)
IP: Juan V. Esplugues.
GRUPO03-226
HelpGroupsI+D+I (2003, 1year)
IP: Juan V. Esplugues.
GR01-212
Supportresearch groupsOCYTGV2001
IP: Sara Calatayud.
PROJECTSinternational research
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Contrato Marie Curie de la Comisión Europea. Endothelin-3/Endothelin receptor B signaling in the regulation of neural crest item cells migration: therapeutic potential for Hirschsprung’s disease. 2007-2009
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Development cooperationproject(November 1997)Spanish Agency forInternationalCooperation.Decreasedmorbidity andmaternal and infant mortalityinurbanareaofthe city ofQuito.Duration 15months.
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Development cooperationproject(November 1996)Spanish Agency forInternationalCooperation.Effect ofL-argininesupplementationon mortality inurbanchildrenofGuayaquil(Ecuador)Duration 15months.
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JointResearch Project(Programfor Scientific Cooperationwith Latin Americafrom 1994 to 1996)Vascular reactivityinnormalpregnant womenwithpregnancy-inducedhypertension.
Support for the purchase,renovation or upgrading ofscientific-technological equipmentfor research infrastructure.
o IF08/3675. Health Research Fund(2008)
o INF05-GV-088. Generalitat Valenciana. (2005)
o INF03-100. Generalitat Valenciana / Valencian Agencyfor Scienceand Technology (2003)
o INF01-058. Department of Culture, Education and Science(2001)
o INF99-12-129. Department of Culture, Education and Science (1999)
o IN95-0297. NationalHealth andPharmacy (1995)