Research projects funded by the Interministerial Commission on Science and Technology (CICYT)
	
	SAF2013-43441-P
	Modulación de la autofagia epitelial por los macrófagos: relevancia en la reparación mucosa en la enfermedad inflamatoria intestinal (2014, 3 years)
	IP: Mª Dolores Barrachina Sancho and Francisca Sara Calatayud Romero
	 
	SAF2010-2023
	Pathophysiological importance of theHIF-induced geneexpressionininflammatory bowel disease(2011,3 years).  
	IP: M. Dolores Barrachina
	 
	SAF2010-16030
	Study of thecellular and molecular mechanismsthat mediatevasculartoxicityinducedby antiretroviral therapy(2011,3 years)  
	IP:  Ángeles Álvarez
	 
	SAF2007-64201 
	Studyof theCellular and MolecularMechanismsThatMediatevasculartoxicityinducedbyantiretroviraltherapy(2011, 3 years)  
	IP:  M. Dolores Barrachina.
	 
	SAF2007-60021 
	Efectos de los fármacos antirretrovirales sobre la interacción leucocito-endotelio. (2007, 3 years)
	IP:  Ángeles Álvarez.
	 
	SAF2005-01366
	Effectsof antiretroviral drugsonleukocyte-endotheliuminteraction.(2007,3 years)  
	IP:  Juan V. Esplugues.
	 
	SAF2004-06211
	Pathophysiologicalrelevanceofinduciblenitric oxide synthaseinthe developmentofgastric lesionsinduced byNSAIDs(2004,3 years)  
	IP:  M. Dolores Barrachina.
	 
	SAF2004-002600 
	Nitric oxideas a regulatorof gene expressionviainducibletranscriptionfactorhypoxia (HIF): molecular mechanismsand physiologicaland pathological implications(2004,1 year)  
	IP:  Juan V. Esplugues.
	 
	SAF2001-0763
	Actionsof nitric oxide oncell respirationand their involvement intheirpathogenic effects(2001,3 years)  
	IP:  Juan V. Esplugues. 
	 
	SAF 99-0114 
	Neurohormonalregulationofgastric function:role of nitric oxide(1999,3 years)  
	IP:  M. Dolores Barrachina.
	 
	SAF98-0118 
	Roleof nitric oxide inthegastrointestinalresponseto stress:involvementpathophysiological andpharmacologicalbases of action(1998,3 years)  
	IP:  Juan V. Esplugues.
	 
	IFD97-1029
	Programme (ERDF)gastroprotectionbynitroglycerin patch.(1997,3 years)  
	IP:  Juan V. Esplugues 
	 
	DGICYT PM95-0145
	Increased gastric mucosal defense induced by endotoxin and other stressors: Characterization of the role of nitric oxide. (1995, 3 years)
	IP:  Juan V. Esplugues
	 
	SAF95-0472
	Pharmacologicalanalysisofthegastrointestinalactionsnitrovasodilators.(1995,3 years)  
	IP:  Juan V. Esplugues. 
	 
	 
	Research projectsfunded by theHealth Research Fund   
	
	PI14/00312
	Papel de los fármacos anti-VIH en la aparición y/o progresión de la enfermedad de higado graso no alcohólico. (2015, 3 years)
	IP: Juan V. Esplugues Mota y Nadezda Apostolova
	 
	PI13/01025
	Disfunción endotelial-mitocondrial, estrés de retículo y autofagia en la diabetes tipo 2: Implicaciones fisiopatológicas, clínicas y terapeúticas (2014, 3 years).
	IP: Victor Manuel Víctor González
	 
	PI13/00073
	Efecto de la pérdida de peso sobre marcadores de estrés de retículo endoplasmático en la obesidad mórbida: Implicaciones fisiopatológicas y nuevas dianas terapéuticas (2014, 3 years).
	IP: Milagros Rocha Barajas
	 
	 
	PI11/00327 
	Characterization of novelcellular mechanisms ofantiretroviralhepatotoxicity.  
	IP: Juan V. Esplugues Mota
	 
	CB06/04/0071
	Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas - CIBERehd (2006-present) 
	IP:  Juan V. Esplugues.
	 
	FIS PI10/01195.
	Biomedical Research CentreNetwork inthe subject areaofLiver and DigestiveDiseases-CIBERehd(2006-present). 
	IP:  Víctor M. Víctor.
	 
	FIS PI081325
	Toxicidad mitocondrial por fármacos antirretrovirales: Caracterización de un nuevo mecanismo agudo de acción (2008, 3 years) 
	IP:  Juan V. Esplugues
	 
	HelpIII(2009-1010)within theProgramofSupport forYoung ResearchersSupportCIBERehdyoung memberof theCIBERpartnerforhiring aresearch technician(2008). 
	IP:  Ángeles Álvarez.
	 
	FIS PI07/00171.
	Oxidative stress andendothelial dysfunction: role ofnitricoxide(2008,2 years). 
	IP:  Victor M Victor.
	 
	ISupport(2007-2008)ayoung memberof theCIBERpartner.Helpayoung memberof theCIBERpartnerforhiring aresearch technician(2007).  
	IP:  M. Dolores Barrachina
	 
	C03/02 
	HelpsDevelopmentCooperative ResearchThematic Networks.RNIHG.National Networkfor Research inHepatology andGastroenterology(2003,3 years)  
	IP:  Adolfo Benages M. Dolores Barrachina, Sara Calatayud.
	 
	CP03/0024 
	Role of nitric oxidein cellular respirationinnormoxiaand hypoxia:physiological andpathophysiologicalimplications(2004,3 years).  
	IP:  Víctor M. Víctor.
	 
	FISPI02/0461 
	Effectsof leptin onleukocyte-endotheliuminteractions(2002,3 years). 
	IP:  Sara Calatayud.
	 
	FIS 01/1187 
	Mechanismsofnitric oxide signalingin thegastrointestinalfunctionalism: Involvementof the nervous andimmunecomponents(2001,3 years).  
	IP:  Mª Dolores Barrachina. 
	 
	FIS 88-1947 
	Influenceof blood pressurein the genesis ofgastric damageinducedPafacetherand thromboxane A2Duration: 1 year  
	 
	FIS 87-1375  
	Study ofgastricactionblockersofcalcium channels.Duration: 1 year  
	 
	 
	Research projects fundedby the Generalitat Valenciana   
	
	 
	PROMETEOII/2014/035
	Farmacología del tracto digestivo y la inflamación. Programa de ayudas para el desarrollo de actuaciones de I+D por grupos de investigación de excelencia Fase II (2014, 4 años)
	IP: Juan V. Esplugues Mota
	 
	ACOMP/2013/236
	Ayuda complementaria para el proyecto "Caracterización de nuevos mecanismos celulares de heptoxicidad por antirretrovirales" (2013, 1 año)
	IP: Juan V. Esplugues Mota
	 
	PROMETEO/2010/60
	PrometheusProgramforexcellent researchgroups(2010,5 years)  
	IP:  Juan V. Esplugues.
	 
	ACOMP/2010/169 
	Additional aidfor R& Dbythe ValencianRegional Ministryon Education(2010, 1year)  
	IP:  Víctor M. Víctor
	 
	ACOMP/2010/207 
	Additional aidtoprojectantiretroviralmitochondrialtoxicity:characterization of a novelacutemechanismof action.(2010, 1year)  
	IP:  Juan V. Esplugues. 
	 
	ACOMP/2009/194 
	Additional aidtoprojectantiretroviralmitochondrialtoxicity:characterization of a novelacutemechanismof action.(2009, 1year)  
	IP:  Juan V. Esplugues. 
	 
	AP-030/09 
	Study ofcardiovascularadverse effectsinducedby antiretroviral therapy(2009, 1year)  
	IP:  Ángeles Álvarez. 
	 
	ACOMP/2009/009 
	Additional aidfor R& Dbythe ValencianRegional Ministryon Education(2009, 1year)  
	IP:  Víctor M. Víctor.
	 
	GVPRE/2008/216 
	Effectof statins onthetranscriptionfactorHIF-1andendothelininhuman endothelialcellssubjected tohypoxia(2008,1 year)IP:  M. Ángeles Martínez.
	 
	GV/2007/074 
	Systematic studyof the effectof antiretroviral drugsonleukocyte-endotheliuminteractions(2007, 1year)  
	IP:  Ángeles Álvarez.
	 
	GV2006-341 
	Nitroglycerinand nitric oxide:mechanismsof action onmitochondriaand oxidative stress(2006, 1year)  
	IP:  Víctor M. Víctor.
	 
	ACOMP/2007/079 
	Ayuda complementaria al proyecto al proyecto Protección mucosa gastrointestinal: una aproximación integradora desde el óxido nítrico mitocondria y HIF (2007, 1 año) 
	IP:  Juan V. Esplugues. 
	 
	ACOMP/2006-246
	Additional aidto the projectthe projectProtectiongastrointestinalmucosa:an integrative approachfrommitochondrialnitric oxideandHIF(2007, 1year)  
	IP:  Juan V. Esplugues. 
	 
	GVAE06-137 
	Vasculartoxicityof drugs usedin the therapyof AIDS(2006, 1year)  
	IP:  Juan V. Esplugues. 
	 
	GRUPOS 05/043 
	ResearchSupportgroups(2005, 1year)  
	IP:  Juan V. Esplugues.
	 
	GV2004-A-147 
	Effectof nitric oxide oncell respirationandphysiologicaland pathophysiologicalimplications.(2004, 1year)  
	IP:  Víctor M. Víctor
	 
	ACOMP07-297 
	Additional aidtoprojectpathophysiological importance of theinduciblenitric oxidesynthaseingastric lesionsinduced byNSAIDs(2007, 1year)   
	IP:  M. Dolores Barrachina.
	 
	ACOMP06/237 
	Additional aidtoprojectpathophysiological importance of theinduciblenitric oxidesynthaseingastric lesionsinduced byNSAIDs(2006, 1year)  
	IP:  M. Dolores Barrachina.
	 
	GV04B-185 
	Pathophysiologicalrelevanceofinduciblenitric oxide synthaseinthe developmentofgastric lesionsinduced byNSAIDs(2004,2 years)  
	IP:  M. Dolores Barrachina.
	 
	GV04-B-184 
	Actionsof nitric oxide oncell respirationand their involvement intheirpathogenic effects(2004,2 years). .
	IP:  Juan V. Esplugues
	 
	S03/226 
	ProjectExcellenceValencian Agencyfor Scienceand Technology(2003,2 years)  
	IP:  Juan V. Esplugues.
	 
	GRUPO03-226 
	HelpGroupsI+D+I (2003, 1year)  
	IP:  Juan V. Esplugues.
	 
	GR01-212 
	Supportresearch groupsOCYTGV2001   
	IP:  Sara Calatayud.
	 
	 
	PROJECTSinternational research   
	
	 
	- 
		Contrato Marie Curie de la Comisión Europea. Endothelin-3/Endothelin receptor B signaling in the regulation of neural crest item cells migration: therapeutic potential for Hirschsprung’s disease. 2007-2009
 
	            
	- 
		Development cooperationproject(November 1997)Spanish Agency forInternationalCooperation.Decreasedmorbidity andmaternal and infant mortalityinurbanareaofthe city ofQuito.Duration 15months. 
 
	 
	- 
		Development cooperationproject(November 1996)Spanish Agency forInternationalCooperation.Effect ofL-argininesupplementationon mortality inurbanchildrenofGuayaquil(Ecuador)Duration 15months. 
 
	  
	- 
		JointResearch Project(Programfor Scientific Cooperationwith Latin Americafrom 1994 to 1996)Vascular reactivityinnormalpregnant womenwithpregnancy-inducedhypertension. 
 
	 
	 
	Support for the purchase,renovation or upgrading ofscientific-technological equipmentfor research infrastructure.   
	
	o IF08/3675. Health Research Fund(2008) 
	 
	o INF05-GV-088. Generalitat Valenciana. (2005)
	 
	o INF03-100. Generalitat Valenciana / Valencian Agencyfor Scienceand Technology (2003)
	 
	o INF01-058. Department of Culture, Education and Science(2001)
	 
	o INF99-12-129. Department of Culture, Education and Science (1999)
	 
	o IN95-0297. NationalHealth andPharmacy (1995)