| Photo | Surname and name | Address | + info | Biography |
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ARTERO ALLEPUZ, RUBEN DARIO |
(9635) 43028 |
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Dr. Artero is Full Professor of Genetics at the University of Valencia, where he obtained his PhD in Biochemistry. After six years of postdoctoral research on myogenesis at Memorial Sloan Kettering Cancer Center in New York, he returned to Spain in 2002 under the Ramón y Cajal Program and joined the University of Valencia as a faculty member. He heads the Human Translational Genomics Laboratory, whose research focuses on the molecular mechanisms and therapeutic development for rare neuromuscular diseases, including myotonic dystrophy and LGMDD2, as well as rare neurological cancers and genetic syndromes. His group combines patient-derived cells, mouse and Drosophila models, and multi-omics approaches to investigate disease mechanisms and evaluate novel therapeutic strategies. Current research also includes drug repurposing, oligonucleotide-based therapies, and innovative delivery platforms. Dr. Artero has authored more than 93 peer-reviewed scientific publications, supervised 20 doctoral theses, and established extensive national and international research collaborations. He is an inventor on several patents and co-founder of the biotechnology spin-off ARTHEx Biotech. |
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BARRIO ESPARDUCER, ELADIO |
Departament de Genètica Facultat de Ciències Biològiques Dr Moliner, 50 46100 Burjassot - València. i Departament de Biotecnologia, lab 309 Institut d'Agroquímica i Tecnologia dels Aliments CSIC Parc Científic de Paterna Carrer Catedràtic Escardino, 7 46980-PATERNA, Valencia (9635) 44180 |
Biography | ||
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Born in Vinaròs (1961). Professor of Genetics at the School of Biological Sciences. He got a degree in Biological Sciences (Biochemistry) and a Ph.D. in Biology from the University of Valencia, with an extraordinary doctorate award. |
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BRACHO LAPIEDRA, MARIA ALMA |
43018 |
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CRAVA, MARIA CRISTINA |
961625583 |
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CUEVAS TORRIJOS, JOSE MANUEL |
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I obtained my Bachelor's Degree in Biological Sciences in 1997 (University of Valencia, UV) and my PhD in Biological Sciences in 2003 (UV). I then completed a postdoctoral fellowship at the Department of Zoology at the University of Oxford (2004-2006), after which I obtained a Juan de la Cierva contract (UV, 2007-2009). I then joined the Institute of Molecular and Cellular Biology of Plants (IBMCP-CSIC, 2010-2012) on a Jae Doc contract. Over the next three years, I resumed my research work at the UV, although it was not until 2016 that I did so as a Ramón y Cajal Researcher. Since 2021, I have been a Associate Professor at the UV, attached to the Department of Genetics of the Faculty of Biological Sciences, and I carry out my research at the Institute of Integrative Systems Biology (I2SysBio). As part of my teaching work, I have supervised numerous final degree and master's degree projects. I also teach subjects related to genetics, molecular evolution and virology in the Biology Degree and the Master in Virology. I have been Co-Director of the latter since 2024. My field of research focuses on the study of virus evolution, primarily RNA viruses, using tools from population genetics, molecular and cellular biology, phylogenetics, and bioinformatics. To this end, I have conducted experimental and molecular evolution studies on models as diverse as human, animal, plant, and bacterial viruses. In particular, the rise of new mass sequencing technologies has led me to recently focus my work on the analysis of mass sequencing data (NGS) to obtain estimates of viral diversity. Currently, the medium/long-term objectives of my line of research are framed within the fusion of bioinformatic analysis of data generated by NGS with previous methodologies acquired throughout my professional career, such as the study of viruses in cell cultures or phylogenetic analysis. Throughout my professional career, I have participated in more than twenty research projects (three of them as principal investigator). I have published more than 50 research articles, most of them as first author or corresponding author, with some featured in journals such as PLoS Biology, Nature Communications, Nature Microbiology, Molecular Biology and Evolution, and PLoS Genetics. I have also published three book chapters. In addition, I have supervised three doctoral theses (another is in progress). |
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DOMINGO CALAP, PILAR |
(9635) 43261 |
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ESCRICHE SOLER, BALTASAR |
Dep. Genetica. Fac. CC. Biologicas. Av. Vicent Andrés Estellés, 19. 46100-Burjassot.Valencia. SPAIN (9635) 43401 |
Biography | ||
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Baltasar Escriche is the Director of the Master in Research in Molecular and Cellular Biology, and Genetics and Secretary of the Doctoral Program in Biomedicine and Biotechnology at the University of Valencia, and belongs to the BTLab team from the research group of Biotechnological Control of Pests (CBP), http://www.cbp.com.es/. He has a positive evaluation of 5 sexennial research periods and the single transference called the sexennial period. Google Scholar provides him 3504 citations, with 32 value for the h-index and 53 value for the i-index. Several aspects of Bacillus thuringiensis have been studied, with a continuous interest in discovering new bioactive proteins and improving the characterization of the already identified. New agents are essential to be prepared for resistance and to broaden the application of bioagents. The main part of the research has focused on Lepidoptera, because of the most common activity of Bt pesticidal proteins, but research with Coleoptera has also been implemented. Understanding the mode of action of each Bt protein, conventional and new proteins, is the key to their optimal use and preventing the selection of resistant populations. He has spent more than 30 years on this purpose, and still, each day, is finding surprising aspects. He contributed to more than 80 publications, mostly in open access, and 150 meeting presentations that can exemplify some of these aspects. He has participated in or led over 60 projects. In fact, in the last 5 years, he has participated mostly as PI in 14 projects, funded by different sources, including different national and international public institutions, and research agreements with both national and multinational companies. Over this time, it has built a long body of resources, protocols, and collaborations. The problems and science are always global from some point of view, and he has been collaborating with laboratories from the whole world, including ones from developing countries, such as in Latin America or Africa. Funds obtained from The Rockefeller Foundation, the Melinda and Bill Gates Foundation, EU PRIMA program, and specific national programs to collaborate with underdeveloped countries are proof of such a vocation. His involvement in the crop protection field led him to become a member of 5 scientific societies, with the special relevance of the Society for Invertebrate Pathology (SIP), where he served as Secretary/Treasurer and later as President of the Bacteria Division. Moreover, he is interested in the dissemination of the research and was co-organizer of the meetings of the SIP/IOBC societies and one from the Spanish Society of Applied Entomology, which took place in Valencia. He actively collaborates with bulletins of such societies, not only the international ones but also in the national ones, and provides some papers in regular journals of the agricultural sector. The implication with the international companies is evidenced by the contacts but, in addition, he has collaborations with national companies (AFRASA, S.A., PROBELTE, S.A.,…). The contracts were to develop new materials and technology, but in other cases to offer services not present in the market. Another aspect is the technician formation in different methodologies not only by hiring in funded projects but also with tutoring in the laboratory, students from regulated technical studies (Professional Formation), and taking part in specific formation actions. He has been involved in different facets in the formation of young researchers as part of his activities as a university professor, with the remarkable tutoring of 3 or 4 research works per year as undergraduate and master's theses. In addition, he has participated in the evaluation commission of about 10 student research works per year from different levels: undergraduate, Master, Ph.D., but also to evaluate university professor positions. The experience allows some of them to pursue a career in science. The doctoral students tutored by him, including several foreign researchers, obtained a high score in their theses, and all of them have followed research careers in public and private companies or institutions. He is a senior piece of the CBP group that has been built over decades and contributes to keeping and enlarging it. The research line of discovering new pesticide resources and the work on insect resistance has been nationally and internationally validated. In fact, he has reviewed projects from several autonomic, national, and international research agencies. It is remarkable that the collaboration with the DFG (Germany), ARIS (Slovenia), and DLR (Western Balkan) agencies. Moreover, he has been invited to serve as a reviewer of more than 25 journals and has become a member sequentially to the editorial board of 5 journals. Moreover, he has participated as an invited editor for Special Issues related to B. thuringiensis in different journals. |
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ESPINOS ARMERO, CARMEN ANGELES |
Despatx: 6ª Planta, Departament de Genètica, Facultat de Ciències Biològiques (Bloc B) |
Biography | ||
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As a university student (Universitat de València, UV), I belonged to the research team awarded with the prize “Certamen de Jóvenes Investigadores” with a proposal about polymorphisms associated with alcoholism (1993). I got my degree in Biology (1993) and my dissertation about Usher syndrome” (1998) was awarded as the best doctoral thesis by ONCE - UV. With this study, I initiated my career on genetics of rare Mendelian diseases. The main scientific contributions were the characterization of genetic bases of Usher syndrome in clinical series and the estimate of prevalence in Spain. My postdoctoral period started in the Unit of Congenital Bleeding Disorders at the University Hospital La Fe (1998-2003), where I got a fellowship from the Instituto de Salud Carlos III (ISCIII). I collaborated on research lines focused on genetics of hemophilia A and B, coagulation FVII deficiency and von Willebrand disease as a postdoctoral researcher. I participated in the genetic study of cohorts of Spanish patients with several coagulopathies. In 2003, I moved to the Instituto de Biomedicina de Valencia – CSIC where I collaborated with open research lines focused on genetics of ataxias, peripheral neuropathies and movement disorders. I described for the first time the genetic bases of an ultrare disease: uroconase deficiency. I started as a group leader with my Miguel Servet I (MSI, 2009-15), and with the first grants, I initiated my own research lines. In 2014, I was evaluated and obtained the MSII contract as PI (2015-18). My group provided new data to better understand the disease mechanism of Charcot-Marie-Tooth type 4C (CMT4C); to characterize genetics associated with CMT and generate genetic tools for diagnosis; to discover junctophilin as a genetic modifier of CMT2K; and to establish MORC2 as a new gene involved in CMT2Z. I initiated new lines focused on the molecular bases and biomarkers for NBIA (Neurodegeneration with Brain Iron Accumulation) and Wilson’s disease (WD). I participated in the development of a new clinical scale for NBIA patients as well as the description of the genetic bases. My group reported the genetics of clinical series of WD and detected a miRNA profile as biomarkers (patent). During these years as MS researcher and group leader, I got projects funded by public or private institutions such as ISCIII, IRDiRC, CNAG, Foundation La Marató TV3, Foundation Ramón Areces, Foundation Per Amor a l'Art, AFM-Téléthon and EASIGenomics. Recently, I was awarded with my sixth national public project funded by the ISCIII (PI24-00017). Technological development activities, in 2012, I moved my MSI contract to the Hospital U. La Fe where I created the Neurogenetics Platform, a service in which we offered genetic analysis of rare hereditary neuropathies. In 2013, I moved to the CIPF where, do I ran my own group and also worked in the Service of Genomics and Translational Genetics (SGGT), in which I carried out genetic analysis of rare neuropathies. In 2016, we generated a gene panel for hereditary peripheral neuropathies that we traded in the service. I was the SGGT’s director from 2015 until its closing in 2021. In 2024, I obtained a teaching position in the Genetics Department of the University of Valencia where I currently carry out my teaching and research activities. I work close with PAOs (patient advocacy organizations): (1) I belong to the scientific board of the Spanish PAOs on Wilson disease (AEFE Wilson) and ataxias (FEDAES), and I usually collaborate in meetings with others (ADIBI, ASVAH). (2) I am the chair-woman of AITER (consortium with 15 institutions for the Translational Research in Rare Diseases in Valencia). (3) I organize since 2016, the National Conference of Female Researchers in Rare Diseases, which binds science, women and rare diseases, and aims to bring science about rare diseases made by women closer to citizens.
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FERRE MANZANERO, JUAN |
Departament de Genètica Facultat de Biologia, bloc B, 6ª planta 46100-Burjassot (València) (9635) 44506 |
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GARCIA MARTINEZ, JOSE |
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GARCIA PEREZ, MIGUEL ANGEL |
43181 |
Biography | ||
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Dr. Miguel Ángel García Pérez is Full Professor of Genetics at the University of Valencia and a researcher affiliated with the INCLIVA Health Research Institute, where he coordinates the Osteoporosis Genetics Research Group. He is also a member of the Healthy Aging in Women (CARMEN) research group at the University of Valencia. His research focuses on understanding the genetic and molecular basis of osteoporosis and other complex diseases. Throughout his career, he has integrated tools from human genetics, transcriptomics, molecular biology, and immunology to investigate the mechanisms underlying disease susceptibility, bone loss, and fracture risk. His work has contributed to the identification of genetic variants, microRNAs, and biomarkers associated with osteoporosis, with the aim of improving fracture risk prediction and promoting the development of new diagnostic strategies. His research combines basic, translational, and clinical approaches to facilitate the transfer of scientific knowledge into clinical practice. He obtained his PhD in Biological Sciences from the University of Valencia, graduating with the highest distinction (Summa Cum Laude, unanimously awarded). Following a postdoctoral fellowship at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (Strasbourg, France), he completed his specialization in Immunology through a residency program at the University Hospital 12 de Octubre in Madrid. Since 2002, he has carried out his teaching and research activities at the University of Valencia, where he was appointed Associate Professor in 2011 and Full Professor of Genetics in 2022. He has participated in more than twenty competitive research projects, several of them as principal investigator, and is the author of over one hundred scientific publications, including 94 papers in international journals indexed in the Journal Citation Reports, 14 book chapters, and nearly 100 contributions to national and international scientific conferences. He has been awarded five recognized six-year research evaluation periods (sexenios de investigación), and his scientific output has received more than 2,000 citations, with an h-index of 27. In teaching, he is primarily responsible for Human Genetics courses in the Biology and Biochemistry and Biomedical Sciences degree programs, as well as Genetic Pathology in the Master's Degree in Research in Molecular and Cellular Biology and Genetics. He also contributes to other undergraduate and postgraduate courses and has supervised bachelor's theses, master's dissertations, and doctoral theses. He is actively involved in scientific evaluation as a reviewer for international biomedical journals and as a project evaluator for the Spanish State Research Agency (AEI), ACSUCYL, and the Regional Ministry of Health of the Andalusian Government. He maintains collaborations with research groups working in the fields of genetics and bone metabolism. |
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GARCIA ROBLES, INMACULADA ROSA |
963543178 |
Biography | ||
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I have a degree in Chemistry specialising in Biochemistry from the Universitat de València (UV, 1994). I spent 5 months in the Goerlaeus laboratories of the University of Leiden (Netherlands). After graduating, I joined the Department of Genetics of the UV, where I did my doctoral thesis with an FPI Scholarship from the Generalitat Valenciana, obtaining my doctorate in 1999. During that period, I made a short stay (1996) at the Institute of Biotechnology of Cuernavaca (Mexico). I have done postdoctoral stays in different centers of recognized prestige, IATA (CSIC) (1999). Cavanilles Institute of Biodiversity and Evolutionary Biology (UV) (1999-2002) and EMBL (Grenoble, France, 2002-2004), with a Specialization Scholarship in International Organizations. Later I joined the Department of Genetics of the UV, with a postdoctoral fellowship Carmen and Severo Ochoa (2007-2009) and from 2009 to 2012 with a contract as a Senior Research Technician. In 2012 I competed and obtained a position as Associate Professor Dr and in 2017 as University Professor. TEACHING ACTIVITY: Since 1996 I have taught in 21 different subjects, covering undergraduate or undergraduate students from second to master's degree. I have taught these classes in 2 degrees (Biology and Chemistry) and in 6 different degrees: Biochemistry and Biomedical Sciences (· BCB, 5), Biotechnology (BT, 5), Biology (Biol, 1), Double Degree Law-Criminology and Degree in Criminology (DC or C, 4) and in two master's degrees: Master in Molecular, Cellular and Genetic Biology (1) and Master in Bioinformatics (2). I am currently coordinator of external internships of students in companies for the Degree in Biotechnology and I have the Quality Mention as a tutor of these practices. Since March 2018 I am Vice-Dean of Innovation and Quality of the Faculty of Biology. I have directed 13 final degree projects in the degrees of Biochemistry and Biomedical Sciences, Biotechnology and Criminology, 6 Master's Final Projects, and the Doctoral Thesis of Dr. López-Galiano: Identification of miRNAs with predictive value as biomarkers of biotic and abiotic stress in plants of agronomic interest. 26.03.2021 and I am co-directing another. I have recognized three five-year teaching periods EDUCATIONAL INNOVATION ACTIVITIES: Since 2018 I have participated in 12 teaching innovation projects with 6 participations in congresses or educational days RESEARCH CAREER: In my research career I have mainly addressed the field of pathogen-host interactions from a multitude of approaches, both in terms of the range of organisms (bacteria-insects, phages-bacteria, insects-plants, viruses-humans) and the type of approach, from purely molecular and basic research (phage structures, protein-protein interactions or biochemical characterization of the mode of action of toxins) to those of clinical or field application. I have recognized three six-year periods of research. In 2014, I participated in the Potato Beetle genome annotation project, within the i5k initiative: genome sequencing of 5000 arthropods. TRANSFER ACTIVITY: I am co-inventor of two patents: P0201030569- Increase in the expression of recombinant sequences in eukaryotes and ES27176855- Peptide and pharmaceutical compositions of the same for use as an antimicrobial and in the treatment of cancer. I have participated in the Innosalud (2020) and Innotransfer (2020, 2021) programs . PEER REVIEW AND EVALUATION ACTIVITIES Since 2009 I have participated as a reviewer in: Letters in Applied Microbiology, Journal of Applied Microbiology, Cells, Plant Cell Reports, IJMS, BAOJ Biotechnology ... I participate as an external Evaluator for the National Agency for Evaluation and Foresight (ANEP) since 2015, for the Valencian Institute of Business Competitiveness (IVACE) since 2019 (21 business projects evaluated) and for the UV-Ministry of Universities, for the evaluation of the University Requalification System program (2021). DISSEMINATION ACTIVITIES. Member of the Organizing Committee of Climathon-Burjassot 2019 (Climate Kick-UV), and Hackaton AgrotecUV (2021). Member of the organizing committee and the scientific congress (Innocampus-Explora project) Innocovid19 (2020) and Innofuturo (2021 ). |
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GASMI, LAILA |
963543616 |
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GIL GARCIA, ROSARIO |
Grup de Genètica Evolutiva, despatx 3.2.3 Institut de Biologia Integrativa de Sistemes (I2SysBio), Parc Científic de la Universitat de València, edifici 4 C/ Catedràtic Agustín Escardino, 9 46980 Paterna (València) (9635) 43824 |
Biography | ||
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PhD in Pharmacy from the Universitat de València (1991), I did a postdoctoral stay of more than 3 years at the Eccles Institute of Human Genetics (University of Utah, USA). After 15 years dedicated to the study of the yeast Saccharomyces cerevisiae from almost any point of view (study of the cell wall, model system for the study of human tumor suppressor genes, analysis of stress and contamination in brewing yeast or global gene expression in wine yeasts), I joined the field of bacterial genomic evolution, in which I have been working since 2001 as a member of the Evolutionary Genetics group of the Universitat de València, where I am currently Full Professor of Genetics. I do my research at the Institute for Integrative Systems Biology (I2SysBio), a joint collaborative center Universitat de València - CSIC. Since 2001, my work has been mainly devoted to the study of the genome of endosymbiotic bacteria, which live inside specialized cells of insect with restricted diets (such as aphids, weevils or mealybugs), to understand the relationship between these bacteria and their hosts, the bacterial genome reduction in these conditions, and its consequences for the inferred metabolic network. As a complement to these studies, I have also been involved in studies on the definition of the minimal genome, essential for the maintenance of a living cell, and its implications in the field of Synthetic Biology. In recent years, our consolidated model system to study symbiotic interactions is the German cockroach Blattella germanica. Cockroaches are specially interesting because two symbiotic systems coexist in each individual, an obligate endosymbiont and a complex gut microbiota. We have developed strategies to better understand the implication of each sytem in the host welfare, and their putative crosstalk. More recently, we are focusing on the host mechanisms to control the symbionts, with special interest in antimicrobial peptides and microRNAs. - Host-symbiont communication and its utility in biological pest and pathogen control (SYMB-CONTROL, PID2021-128201NB-I00; co-financed MICIN-UEFEDER-AEI, EU and Spain)
Recent and selected publications Cazzaniga, M., R. Domínguez-Santos, J. Marín-Miret, R. Gil, A. Latorre, C. García-Ferris (2023). Exploring gut microbial dynamics and symbiotic interaction in Blattella germanica using rifampicin. Biology 12:955. doi: 10.3390/biology12070955 Latorre, A., R. Domínguez-Santos, C. García-Ferris, R. Gil (2022). Of cockroaches and symbionts: recent advances in the characterization of the relationship between Blattella germanica and its dual symbiotic system. Live 12: 290. doi: 10.3390/life12020290 Garzón, M.J., M. Reyes-Prieto, R Gil (2022). The minimal translation machinery: what we can learn from naturally and experimentally reduced genomes. Front. Microbiol. 13:858983. doi: 10.3389/fmicb.2022.858983 Solana, J., E. Garrote-Sánchez, R. Gil (2021). DELEAT: gene essentiality prediction and deletion design for bacterial genome reduction. BMC Bioinformatics 22:444. doi: 10.1186/s12859-021-04348-5 Domínguez-Santos R, A.E. Pérez-Cobas, P. Cuti, V. Pérez-Brocal, C. García-Ferris, A. Moya, A. Latorre, R. Gil (2021). Interkingdom gut microbiome and resistome of the cockroach Blattella germanica. mSystems 6:e01213-20. doi: 10.1128/mSystems.01213-20 Reyes-Prieto, M., R. Gil, M. Llabrés, P. Palmer-Rodríguez, A. Moya (2021). The metabolic building blocks of a minimal cell. Biology, 10:5. doi: 10.3390/biology10010005 Gil, R., A. Latorre (2019). Unity makes strength: a review on mutualistic symbiosis in representative insect clades. Life 9: 21; doi:10.3390/life9010021. Gil, R., C. Vargas-Chavez, S. López-Madrigal, D. Santos-García, A. Latorre, A. Moya (2018). Tremblaya phenacola PPER: An evolutionary beta-gammaproteobacterium collage. ISME J. 12:124-135. doi: 10.1038/ismej.2017.144 López-Madrigal, S., R. Gil (2017). Et tu, Brute? Not even intracellular mutualistic symbionts escape horizontal gene transfer. Genes 8:247. doi: 10.3390/genes8100247 Lloréns-Rico, V., J. Cano, T. Kamminga, R. Gil, A. Latorre, W. H. Chen, P. Bork, J. I. Glass, L. Serrano, M. Lluch-Senar (2016). Bacterial antisense RNAs are mainly the product of transcriptional noise. Sci. Adv. 2:e1501363. doi: 10.1126/sciadv.1501363 Klein, A., L. Schrader, R. Gil, A. Manzano-Marín, L. Flórez, D. Wheeler, J. H. Werren, A. Latorre, J. Heinze, M. Kaltenpoth, A. Moya, J. Oettler (2016). A novel intracellular mutualistic bacterium in the invasive ant Cardiocondyla obscurior. ISME J. 10:376-388. doi: 10.1038/ismej.2015.119 Gil, R., J. Peretó (2015). Small genomes and the difficulty to define minimal translation and metabolic machineries. Front. Ecol. Evol. 3:123. doi: 10.3389/fevo.2015.00123 López-Madrigal, S., A. Latorre, A. Moya, R. Gil (2015). The link between independent acquisition of intracellular gamma-endosymbionts and concerted evolution in Tremblaya princeps. Front. Microbiol. 6:642. doi: 10.3389/fmicb.2015.00642 Gil, R. (2014). The minimal gene-set machinery. In Encyclopedia of Molecular Cell Biology and Molecular Medicine: Synthetic Biology, 2nd edition. Meyers RA (ed.). Wiley-VCH Verlag GmbH & Co. pp. 1-36. doi: 10.1002/3527600906.mcb.20130079 López-Madrigal, S., A. Beltrà, S. Resurrección, A. Soto, A. Latorre, A. Moya, R. Gil (2014). Molecular evidence for ongoing complementarity and horizontal gene transfer in endosymbiotic systems of mealybugs. Front. Microbiol. 5:449. doi: 10.3389/fmicb.2014.00449 Oakeson, K. F.*, R. Gil*, A. L. Clayton, D. M. Dunn, A. C. von Niederhausern, C. Hamil, A. Aoyagi, B. Duval, A. Baca, F.J. Silva, A. Vallier, D. G. Jackson, A. Latorre, R. B. Weiss, A. Heddi, A. Moya, C. Dale (2014). Genome degeneration and adaptation in a nascent stage of symbiosis. Genome Biol. Evol. 6:76-93. doi: 10.1093/gbe/evt210 *Equal contribution. López-Madrigal, S., A. Latorre, M. Porcar, A. Moya, R. Gil (2013). Mealybugs nested endosymbiosis: going into the ‘matryoshka’system in Planococcus citri in depth. BMC Microbiol. 13:74. doi: 10.1186/1471-2180-13-74 Moya, A., R. Gil, A. Latorre., J. Peretó, M.P. Garcillán-Barcia, F. de la Cruz (2009). Towards minimal bacterial cells: evolution versus design. FEMS Microbiol. Rev. 33:225-235. doi: 10.1111/j.1574-6976.2008.00151.x Moya, A., J. Peretó, R. Gil, A. Latorre (2008). Learning how to live together: genomic insights into prokaryote-animal symbioses. Nature Rev. Genet. 9:218-229. doi:10.1038/nrg2319 Tamames, J.*, R. Gil*, A. Latorre, J. Peretó, F.J. Silva, A. Moya (2006). The frontier between cell and organelle: genome analysis of Candidatus Carsonella ruddii. BMC Ecol. Evol. 7:181. doi: 10.1186/1471-2148-7-181 *Equal contribution. T. Gabaldón, J. Peretó, F. Montero, R. Gil, A. Latorre, A. Moya (2007). Structural analyses of a hypothetical minimal metabolism. Phil. Trans. R. Soc. B. Biol. Sci. 362:1751-1762. doi: 10.1098/rstb.2007.2067 Pérez-Brocal, V., R. Gil, S. Ramos, A. Lamelas, M. Postigo, J. M. Michelena, F. J. Silva, A. Moya, A. Latorre (2006). A small microbial genome: the end of a long symbiotic relationship? Science 314:312-313. doi: 10.1126/science.1130441 Gil, R., F. J. Silva, J. Peretó, A. Moya (2004). Determination of the core of the minimal bacterial gene set. Microbiol. Mol. Biol. Rev. 68: 518-537. doi: 10.1128/MMBR.68.3.518-537.2004 Gil, R., B. Sabater-Muñoz, A. Latorre, F. J. Silva, A. Moya (2002). Extreme genome reduction in Buchnera spp.: towards the minimal genome needed for symbiotic life. Proc. Natl. Acad. Sci. USA 99: 4454-4458. doi: 10.1073/pnas.062067299 |
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GONZALEZ CABRERA, JOEL |
(9635) 43122 |
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English I obtained my degree in Biochemistry from the University of Havana (Cuba) in 1996. I began my scientific career at the Centre for Genetic Engineering and Biotechnology in Havana, where I worked on the development of transgenic plants expressing Bacillus thuringiensis (Bt) toxins. Between 1998 and 2012, I held research positions at several Spanish institutions, including the Universitat de València, the Instituto Valenciano de Investigaciones Agrarias and the Centro de Investigaciones Biológicas. I obtained my PhD in 2004 and carried out postdoctoral research focused on the molecular characterization of resistance mechanisms to Bt toxins and on the study of toxin–receptor interactions. During this period, I also investigated the integration of Bt-based technologies with biological control agents for the sustainable management of economically important pests within Integrated Pest Management (IPM) programmes. In 2012, I joined Rothamsted Research (United Kingdom) as a Marie Curie Fellow. My research addressed the mode of action and selectivity of pyrethroids in economically important mites and ticks, as well as resistance mechanisms to other compounds, including flumethrin, coumaphos and amitraz. In addition, I developed sensitive molecular tools and monitoring assays for applications in IPM programmes. In 2015, I joined the BIOTECMED Institute at the Universitat de València (Spain) as a Ramón y Cajal Research Fellow, and since 2021 I have held a position as Associate Professor. My research focuses on understanding the evolutionary and molecular mechanisms underlying pesticide resistance and identifying the determinants governing pesticide selectivity towards non-target organisms. I am also interested in the ecological and evolutionary processes that influence the long-term efficacy and sustainability of biological control programmes. |
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GONZALEZ CANDELAS, FERNANDO |
Despacho 2.6.I Instituto de Biología Integrativa de Sistemas, I2SysBio (CSIC-UV). Parc Científic. Paterna. (9635) 43653 |
Biography | ||
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Fernando Gonzalez Candelas, PhD (University of Valencia, 1987) is Professor of Genetics at the University of Valencia since 2006 and head of the “Evolution and Health” Research Unit at the Institute for Integrative Systems Biology UV-CSIC (I2SysBio) at the same university. In addition, he has a joint appointment at the FISABIO-Public Health through the joint research unit “Infection and Public Health” with the University of Valencia and at the CIBERESP (Centre for Networked Research on Biomedicine – Public Health and Epidemiology). |
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HERNANDEZ MARTINEZ, PATRICIA |
Instituto BioTecMed; Fac. Ciencias Biológicas Dpto Genética, 6º piso edificio B Dr Moliner 50, 46100 Burjassot (Valencia) 96 1625583 (D) |
Biography | ||
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[I studied Biology (1998-2003) and obtained my PhD in Biology at the University of Valencia (UV), Spain, in 2009. After my PhD, I worked as an associate researcher for 14 years in the Department of Genetics at UV continuing with the same line of research from my PhD. Finally in 2023, I became a Doctor Assistant in the area of genetics. My research is associated with the Institute of Biotechnology and Biomedicine at UV (Biotecmed). My current research interests are (a) studying the mode of action of Bacillus thuringiensis (Bt) proteins, (b) studying the response mechanism of different hosts after challenge with Bt proteins, (c) and understanding the biochemical and genetic basis of resistance of agricultural insect pests to Bt proteins.Biography, english version] |
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HERRERO SENDRA, SALVADOR |
(9635) 43006 |
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LOPEZ CASTEL, ARTURO |
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LUCAS LLEDO, JOSE IGNACIO |
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PALMA DOVIS, LEOPOLDO |
Departament de Genètica Facultat de Biologia, bloc B, 6ª planta 46100-Burjassot (València) 963544297 (D) |
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[ Automatic translation ]
I obtained my PhD in Biotechnology at the Public University of Navarra, in the laboratory of Prof. Primitivo Caballero, where I worked on Bacillus thuringiensis and its insecticidal proteins. Later I was a professor at the National University of Villa María (UNVM) and Associate Researcher at the National Scientific and Technical Research Council (CONICET, Argentina), focusing my research on the identification and characterization of autochthonous strains ofB. thuringiensiswith new insecticidal activities. In 2022 I joined the Universitat de València with a María Zambrano Distinguished Researcher contract, joining the Biotechnological Pest Control group, where my research focused on the study of Bt Vip insecticidal protein receptors. Since 2025 I have been a Ramón y Cajal Researcher at the Universitat de València (UV), developing a new line of research based on the study of nematodes indigenous entomopathogens and their symbiotic bacteria. |
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MARTINEZ TORRES, DAVID |
(9635) 43644 |
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[Biography, english version] |
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MOLTO RUIZ, MARIA DOLORES |
(9635) 43400 |
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MOYA SIMARRO, ANDRES |
Integrative Systems Biology Institute (I2Sysbio); University of València and Spanish Research Council (CSIC); c/ Catedrático José Beltrán 2, 46980 Paterna, València, Spain. Foundation for the Promotion of Sanitary and Biomedical Research of Valencian Community (FISABIO); Avenida de Cataluña 21, 42... (9635) 43480 |
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He studied Biology and Philosophy simultaneously at the University of Valencia, obtaining his Ph.D. in Biology in 1983 and Philosophy (Extraordinary Award) in 1988. He did his postdoctoral stay in 1985-1986 with a Fulbright grant at the University of California at Davis (USA). He had been visiting professor at the University of California at Irvine (USA) in 1988 and 1994, and in 2019 professor on a sabbatical stay with a Fulbright grant at Harvard University. In 1986 he created the Evolutionary Genetics group in the Dept. of Genetics at the University of Valencia, where he has been a professor since 1993. He was the director of this Dept. from 1995 to 1998. He has been the promoter of the Cavanilles Institute of Biodiversity and Evolutionary Biology of the University of Valencia and its director from its creation in 1998 until 2010. He has also been a promoter of the Astrobiology Center (INTA-CSIC) and the Centro Superior de Investigación en Salud Pública de la Conselleria de Sanidad del Gobierno Valenciano (CSISP), of which he was its director in 2012. The CSISP was integrated into the Valencian Foundation for Promoting Health and Biomedical Research of the Valencian Community, FISABIO. He was the FISABIO-Public Health division's scientific director from 2013 until July 2014. Since August 2014, he has directed, within FISABIO, the FISABIO Chair for the Promotion of Biomedical Research, an Institutional Chair of the University of Valencia. He is the author of about 600 publications, including scientific articles, reviews, book chapters, and books on Genetics, Evolution, and Philosophy (20,700 citations, h-index of 74). He has participated in several patents and created a spin-off company. Experimental evolution of viruses and genomics and metagenomics of bacteria and microbial communities represent the research areas where he has made the most significant scientific contributions. He introduced Genomics in Spain, and his group sequenced the first genome of a bacterium, entirely carried out in Spain. He has done extensive work in disseminating and reflecting on science and has published several books on evolutionary theory and the scope of evolutionary thought. He currently focuses his research on symbiosis, mainly studying the human microbiome and other organisms from an evolutionary, systems biology, and synthetic biology perspective. He has supervised 35 doctoral theses, and many national and foreign scientists have been trained in his research group. He has received competitive funding from regional, national, European, and international agencies and has been the principal investigator of national, European, and international projects. He has given lectures and courses in European countries, Latin America, the United States, and Asia. He has formed or is a member of commissions of research evaluation agencies in Spain and its autonomous communities, different European and Latin American countries, and the European Union. He is a member of several scientific societies, founder of the European Society of Evolutionary Biology, the Spanish Society of Virology, and the Spanish Society of Evolutionary Biology, of which he has been its president. He is editor-in-chief, associate editor, or editorial board member of several scientific and philosophical journals. He has received the following distinctions: the City of Barcelona Award for Scientific Research (1996), "Fellow" of the "American Association for the Advance of Science" (1998), the Diario Médico Award (2006), Diploma of the President of the Valencian Government for Excellence in Biomedical Research (2010), National Genetics Award (2012), Lilly Award in Preclinical Biomedical Research (2013), Mexico Award for Science and Technology (2015), Dr. Honoris Causa by the Menéndez Pelayo International University (2016), Advisor to the Gadea Foundation (2017), Maestro Andrés Laguna Award (2019), Alberto Sols Award for Research in Health Sciences (2022). |
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OLTRA SOLER, JUAN SILVESTRE |
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PARICIO ORTIZ, NURIA |
(9635) 43005 |
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PEREZ ALONSO, MANUEL |
Departamento de Genética Facultad de Biología (Bloque B, 6º piso) Campus de Burjasot (9635) 43179 |
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RAUSELL SEGARRA, CAROLINA |
(9635) 43397 |
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I initiated my research activity with a FPI pre-doctoral grant from the Spanish Ministry of Education (1994-1997) to carry out the PhD Thesis entitled “Mode of action of Bacillus thuringiensis insecticidal proteins in the forests pests Thaumetopoea pityocampa and Lymantria monacha” supervised by Dr. M. Dolores Real at the University of Valencia During this period, I performed a three-month research stay at the biotechnological company Plant Genetic Sytems (Ghent, Belgium) in 1993, and a two-month research stay at the Entomology Department of the Ludwig Maximilians Universität (München, Germany) in 1995. I started my post-doctoral research (1998-2001) in the research group of Dr. Andrés Moya and Dr. Amparo Latorre on the area of insect endosymbionts genome sequencing at the Astrobiology Center (INTA, Madrid) and Cavanilles Institute of Biodiversity and Evolutionary Biology (University of Valencia), followed by a post-doctoral research stay (2002-2004) at Dr. Alejandra Bravo’s laboratory (Biotechnology Institute, UNAM, Mexico), focused on the molecular mechanisms of membrane insertion of B. thuringiensis toxins. In 2004, I rejoined Dr. M. Dolores Real’s group at the Genetics Department of the University of Valencia with a “Ramón y Cajal” research contract (2004-2009) to study Cry3Aa toxin mode of action in coleopteran pests. Since 2009, I am associate professor of Genetics at the University of Valencia and I have expanded my research in the area of plant protection to include the study and characterization of the underlying molecular mechanisms of plant defense against biotic and abiotic stress as well as exploiting natural resources (natural priming compounds, insect microbial communities, peptides of plant or insect origin) to improve plant performance. After a two-month research stay that I performed at Dr. Hoskins’ laboratory (Pathology Dept., Dalhousie University, Canada) in 2015, our group started a new line of research on the use of peptides derived from insects as antimicrobial agents and in cancer, and I am co-inventor of the patent entitled “Peptide and pharmaceutical compositions of same for use as antimicrobial and in cancer treatment” (ES201731455, PCT/ES2018/070824). I am full professor of Genetics since 2025. As a researcher I have participated in 16 research projects, being PI and co-PI of 6 of them, and I have 5 “sexenios” (six year-research periods) recognized. Throughout my scientific career I have participated in several international projects supported by funding organizations for research and innovation networks such as COST and CYTED and I have also carried out research in collaboration with companies such as with Ionera Technologies GmbH, Freiburg, Germany. From 2020 to 2024, our research group participated in the European project “SYSTEMIC: An integrated approach to the challenge of sustainable food systems: adaptive and mitigatory strategies to address climate change and malnutrition”, within the ERA-HDHL Knowledge Hub on Food and Nutrition Security in which I was co-leader of WP 2 Task 1 “Crop production optimization, biodiversity, and plant breeding”. I have co-directed 3 PhD theses (Camila Ochoa, 2011; Estefanía Contreras, 2013; Aida Robles Fort, 2023), two of which were granted with the Extraordinary Doctorate Award, as well as 8 Master theses. I have also served as reviewer of several scientific journals (Journal of Invertebrate Pathology, Insect Biochemistry and Molecular Biology, etc.). |
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REAL GARCIA, MARIA DOLORES |
(9635) 43397 |
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SANJUAN VERDEGUER, RAFAEL |
(9635) 43270 |
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