Photo | Name and surname | Address | + info | Biography |
---|---|---|---|---|
ARTERO ALLEPUZ, RUBEN DARIO |
(9635) 43028 |
Biography | ||
My academic formation is biochemistry. I did my thesis under Prof. Manuel Pérez Alonso's guidance, which led to the identification of the Drosophila gene muscleblind, the founder member of the Muscleblind-like (MBNL) family of alternative splicing regulators with critical roles in human genetic diseases such as myotonic dystrophy. After 6 years of postdoctoral training in Mary Baylies' laboratory at the Memorial Sloan-Kettering Cancer Center in New York, in 2001 I returned to Spain with a Ramón y Cajal research contract and started my independent research career at the University of Valencia where my overarching goal is to understand the mechanisms of pathogenesis and to discover therapeutic targets and innovative treatments of human genetic diseases, with a particular focus in myotonic dystrophy. To this end, we use human samples and animal and cell models to understand the molecular basis of disease, perform drug repurposing screenings, and evaluate the activity of oligonucleotide-based drugs. We actively seek a close relationship with clinical researchers and biotech companies. |
||||
BARRIO ESPARDUCER, ELADIO Director/a de Servei General |
Servei Central de Suport a la Investigació Experimental Edifici d'Investigació Dr Moliner, 50 46100 Burjassot - València. Departament de Biotecnologia, lab 309 Institut d'Agroquímica i Tecnologia dels Aliments CSIC Parc Científic de Paterna Carrer Catedràtic Escardino, 7 46980-PATERNA,... (9635) 44180 |
Biography | ||
Born in Vinaròs (1961). Professor of Genetics at the School of Biological Sciences. He got a degree in Biological Sciences (Biochemistry) and a Ph.D. in Biology from the University of Valencia, with an extraordinary doctorate award. |
||||
BRACHO LAPIEDRA, MARIA ALMA |
961925969 (D) |
|||
CRAVA, MARIA CRISTINA |
961625583 |
|||
ESCRICHE SOLER, BALTASAR Director/a Titulacio Master Oficial |
(9635) 43401 |
|||
FERRE MANZANERO, JUAN Director/a d' Institut Universitari |
Departament de Genètica Facultat de Biologia, bloc B, 6ª planta 46100-Burjassot (València) (9635) 44506 |
|||
GARCIA MARTINEZ, JOSE Director/a de Departament |
||||
GARCIA PEREZ, MIGUEL ANGEL |
43181 |
|||
GARCIA ROBLES, INMACULADA ROSA Vicedega/Vicedegana / Vicedirector/a Ets |
963543178 |
Biography | ||
I have a degree in Chemistry specialising in Biochemistry from the Universitat de València (UV, 1994). I spent 5 months in the Goerlaeus laboratories of the University of Leiden (Netherlands). After graduating, I joined the Department of Genetics of the UV, where I did my doctoral thesis with an FPI Scholarship from the Generalitat Valenciana, obtaining my doctorate in 1999. During that period, I made a short stay (1996) at the Institute of Biotechnology of Cuernavaca (Mexico). I have done postdoctoral stays in different centers of recognized prestige, IATA (CSIC) (1999). Cavanilles Institute of Biodiversity and Evolutionary Biology (UV) (1999-2002) and EMBL (Grenoble, France, 2002-2004), with a Specialization Scholarship in International Organizations. Later I joined the Department of Genetics of the UV, with a postdoctoral fellowship Carmen and Severo Ochoa (2007-2009) and from 2009 to 2012 with a contract as a Senior Research Technician. In 2012 I competed and obtained a position as Associate Professor Dr and in 2017 as University Professor. TEACHING ACTIVITY: Since 1996 I have taught in 21 different subjects, covering undergraduate or undergraduate students from second to master's degree. I have taught these classes in 2 degrees (Biology and Chemistry) and in 6 different degrees: Biochemistry and Biomedical Sciences (· BCB, 5), Biotechnology (BT, 5), Biology (Biol, 1), Double Degree Law-Criminology and Degree in Criminology (DC or C, 4) and in two master's degrees: Master in Molecular, Cellular and Genetic Biology (1) and Master in Bioinformatics (2). I am currently coordinator of external internships of students in companies for the Degree in Biotechnology and I have the Quality Mention as a tutor of these practices. Since March 2018 I am Vice-Dean of Innovation and Quality of the Faculty of Biology. I have directed 13 final degree projects in the degrees of Biochemistry and Biomedical Sciences, Biotechnology and Criminology, 6 Master's Final Projects, and the Doctoral Thesis of Dr. López-Galiano: Identification of miRNAs with predictive value as biomarkers of biotic and abiotic stress in plants of agronomic interest. 26.03.2021 and I am co-directing another. I have recognized three five-year teaching periods EDUCATIONAL INNOVATION ACTIVITIES: Since 2018 I have participated in 12 teaching innovation projects with 6 participations in congresses or educational days RESEARCH CAREER: In my research career I have mainly addressed the field of pathogen-host interactions from a multitude of approaches, both in terms of the range of organisms (bacteria-insects, phages-bacteria, insects-plants, viruses-humans) and the type of approach, from purely molecular and basic research (phage structures, protein-protein interactions or biochemical characterization of the mode of action of toxins) to those of clinical or field application. I have recognized three six-year periods of research. In 2014, I participated in the Potato Beetle genome annotation project, within the i5k initiative: genome sequencing of 5000 arthropods. TRANSFER ACTIVITY: I am co-inventor of two patents: P0201030569- Increase in the expression of recombinant sequences in eukaryotes and ES27176855- Peptide and pharmaceutical compositions of the same for use as an antimicrobial and in the treatment of cancer. I have participated in the Innosalud (2020) and Innotransfer (2020, 2021) programs . PEER REVIEW AND EVALUATION ACTIVITIES Since 2009 I have participated as a reviewer in: Letters in Applied Microbiology, Journal of Applied Microbiology, Cells, Plant Cell Reports, IJMS, BAOJ Biotechnology ... I participate as an external Evaluator for the National Agency for Evaluation and Foresight (ANEP) since 2015, for the Valencian Institute of Business Competitiveness (IVACE) since 2019 (21 business projects evaluated) and for the UV-Ministry of Universities, for the evaluation of the University Requalification System program (2021). DISSEMINATION ACTIVITIES. Member of the Organizing Committee of Climathon-Burjassot 2019 (Climate Kick-UV), and Hackaton AgrotecUV (2021). Member of the organizing committee and the scientific congress (Innocampus-Explora project) Innocovid19 (2020) and Innofuturo (2021 ). |
||||
GIL GARCIA, ROSARIO Coordinador/a de Programa de Doctorat |
Grup de Genètica Evolutiva, despatx 3.2.3 Institut de Biologia Integrativa de Sistemes (I2SysBio), Parc Científic de la Universitat de València, edifici 4 C/ Catedràtic Agustín Escardino, 9 46980 Paterna (València) (9635) 43824 |
Biography | ||
PhD in Pharmacy from the Universitat de València (1991), I did a postdoctoral stay of more than 3 years at the Eccles Institute of Human Genetics (University of Utah, USA). After 15 years dedicated to the study of the yeast Saccharomyces cerevisiae from almost any point of view (study of the cell wall, model system for the study of human tumor suppressor genes, analysis of stress and contamination in brewing yeast or global gene expression in wine yeasts), I joined the field of bacterial genomic evolution, in which I have been working since 2001 as a member of the Evolutionary Genetics group of the Universitat de València, where I am currently Associate Professor of Genetics. I do my research at the Institute for Integrative Systems Biology (I2SysBio), a joint collaborative center Universitat de València - CSIC. My current work focuses on the study of the genome of endosymbiotic bacteria, which live inside specialized cells of insect with restricted diets (such as aphids, weevils or mealybugs), to understand the relationship between these bacteria and their hosts, the bacterial genome reduction in these conditions, and its consequences for the inferred metabolic network. As a complement to these studies, I am also involved in studies on the definition of the minimal genome, essential for the maintenance of a living cell, and its implications in the field of Synthetic Biology. In this sense, in recent years we have started a new research line in which we use the bacterial species Bartonella quintana as an endosymbiotic model for the design of a chassis that can be used in Synthetic Biology for therapeutic purposes. Current research projects Basic and applied approaches to unravel and modify model symbiotic systems. PGC2018-099344-B-I00 (co-financed by FEDER funds and Ministerio de Ciencia, Innovación y Universidades, Spain) Evolution, experimental epidemiology and therapeutic engineering of the microbiota. PROMETEO/2018/133 (Generalitat Valenciana, Spain).
Recent and selected publications Solana, J., E. Garrote-Sánchez and R. Gil (2021). DELEAT: gene essentiality prediction and deletion design for bacterial genome reduction. BMC Bioinformatics 22:444. doi:10.1186/s12859-021-04348-5 https://doi.org/10.1186/s12859-021-04348-5 Domínguez-Santos, R., A. E. Pérez-Cobas, P. Cuti, V. Pérez-Brocal, C. García-Ferris, A. Moya, A. Latorre, R. Gil (2021). Interkingdom gut microbiome and resistome of the cockroach Blattella germanica. mSystems 6:e01213-20. doi: 10.1128/mSystems.01213-20 Reyes-Prieto, M., R. Gil, M. Llabrés, P. Palmer-Rodríguez, A. Moya (2021). The metabolic building blocks of a minimal cell. Biology, 10:5. doi: 10.3390/biology10010005 Gil, R., A. Latorre (2019). Unity makes strength: a review on mutualistic symbiosis in representative insect clades. Life 9: 21; doi:10.3390/life9010021. Gil, R., C. Vargas-Chavez, S. López-Madrigal, D. Santos-García, A. Latorre, A. Moya (2018). Tremblaya phenacola PPER: An evolutionary beta-gammaproteobacterium collage. ISME J. 12:124-135. doi: 10.1038/ismej.2017.144 López-Madrigal, S., R. Gil (2017). Et tu, Brute? Not even intracellular mutualistic symbionts escape horizontal gene transfer. Genes 8:247. doi: 10.3390/genes8100247 Lloréns-Rico, V., J. Cano, T. Kamminga, R. Gil, A. Latorre, W. H. Chen, P. Bork, J. I. Glass, L. Serrano, M. Lluch-Senar (2016). Bacterial antisense RNAs are mainly the product of transcriptional noise. Sci. Adv. 2:e1501363. doi: 10.1126/sciadv.1501363 Klein, A., L. Schrader, R. Gil, A. Manzano-Marín, L. Flórez, D. Wheeler, J. H. Werren, A. Latorre, J. Heinze, M. Kaltenpoth, A. Moya, J. Oettler (2016). A novel intracellular mutualistic bacterium in the invasive ant Cardiocondyla obscurior. ISME J. 10:376-388. doi: 10.1038/ismej.2015.119 Martínez-Díaz, V., A. Latorre, R. Gil (2016). Seasonal changes in the endosymbiotic consortia of aphids from the genus Cinara. Microbes Environ. 31:137-144. doi: 10.1264/jsme2.ME15118 Gil, R., J. Peretó (2015). Small genomes and the difficulty to define minimal translation and metabolic machineries. Front. Ecol. Evol. 3:123. doi: 10.3389/fevo.2015.00123 López-Madrigal, S., A. Latorre, A. Moya, R. Gil (2015). The link between independent acquisition of intracellular gamma-endosymbionts and concerted evolution in Tremblaya princeps. Front. Microbiol. 6:642. doi: 10.3389/fmicb.2015.00642 Gil, R. (2014). The minimal gene-set machinery. In Encyclopedia of Molecular Cell Biology and Molecular Medicine: Synthetic Biology, 2nd edition. Meyers RA (ed.). Wiley-VCH Verlag GmbH & Co. pp. 1-36. doi: 10.1002/3527600906.mcb.20130079 López-Madrigal, S., A. Beltrà, S. Resurrección, A. Soto, A. Latorre, A. Moya, R. Gil (2014). Molecular evidence for ongoing complementarity and horizontal gene transfer in endosymbiotic systems of mealybugs. Front. Microbiol. 5:449. doi: 10.3389/fmicb.2014.00449 Oakeson, K. F.*, R. Gil*, A. L. Clayton, D. M. Dunn, A. C. von Niederhausern, C. Hamil, A. Aoyagi, B. Duval, A. Baca, F.J. Silva, A. Vallier, D. G. Jackson, A. Latorre, R. B. Weiss, A. Heddi, A. Moya, C. Dale (2014). Genome degeneration and adaptation in a nascent stage of symbiosis. Genome Biol. Evol. 6:76-93. doi: 10.1093/gbe/evt210 *Equal contribution. López-Madrigal, S., A. Latorre, M. Porcar, A. Moya, R. Gil (2013). Mealybugs nested endosymbiosis: going into the ‘matryoshka’system in Planococcus citri in depth. BMC Microbiol. 13:74. doi: 10.1186/1471-2180-13-74 Moya, A., R. Gil, A. Latorre., J. Peretó, M.P. Garcillán-Barcia, F. de la Cruz (2009). Towards minimal bacterial cells: evolution versus design. FEMS Microbiol. Rev. 33:225-235. doi: 10.1111/j.1574-6976.2008.00151.x Moya, A., J. Peretó, R. Gil, A. Latorre (2008). Learning how to live together: genomic insights into prokaryote-animal symbioses. Nature Rev. Genet. 9:218-229. doi: 10.1038/nrg2319 Tamames, J.*, R. Gil*, A. Latorre, J. Peretó, F.J. Silva, A. Moya (2006). The frontier between cell and organelle: genome analysis of Candidatus Carsonella ruddii. Science 314:312-313. doi: 10.1186/1471-2148-7-181 *Equal contribution. T. Gabaldón, J. Peretó, F. Montero, R. Gil, A. Latorre, A. Moya (2007). Structural analyses of a hypothetical minimal metabolism. Phil. Trans. R. Soc. B. Biol. Sci. 362:1751-1762. doi: 10.1098/rstb.2007.2067 Pérez-Brocal, V., R. Gil, S. Ramos, A. Lamelas, M. Postigo, J. M. Michelena, F. J. Silva, A. Moya, A. Latorre (2006). A small microbial genome: the end of a long symbiotic relationship? Science 314:312-313. doi: 10.1126/science.1130441 Gil, R., F. J. Silva, J. Peretó, A. Moya (2004). Determination of the core of the minimal bacterial gene set. Microbiol. Mol. Biol. Rev. 68: 518-537. doi: 10.1128/MMBR.68.3.518-537.2004 Gil, R., B. Sabater-Muñoz, A. Latorre, F. J. Silva, A. Moya (2002). Extreme genome reduction in Buchnera spp.: towards the minimal genome needed for symbiotic life. Proc. Natl. Acad. Sci. USA 99: 4454-4458. doi: 10.1073/pnas.062067299 |
||||
GONZALEZ CABRERA, JOEL Delegat/Delegada Rector/A |
(9635) 43122 |
|||
GONZALEZ CANDELAS, FERNANDO |
Despacho 1.5.D Instituto de Biología Integrativa de Sistemas, I2SysBio (CSIC-UV). Parc Científic. Paterna. (9635) 43653 |
Biography | ||
Fernando González Candelas, PhD (University of Valencia, 1987) is Professor of Genetics at the University of Valencia since 2006 and head of the “Evolution and Health” Research Unit at the Institute for Integrative Systems Biology UV-CSIC (I2SysBio) at the same university. In addition, he has a joint appointment at the FISABIO-Public Health through the joint research unit “Infection and Public Health” with the University of Valencia and at the CIBERESP (Centre for Networked Research on Biomedicine – Public Health and Epidemiology). |
||||
HERRERO SENDRA, SALVADOR Director/a Titulacio Master Oficial |
(9635) 43006 |
|||
LOPEZ CASTEL, ARTURO |
||||
MARTINEZ TORRES, DAVID |
(9635) 43644 |
|||
MOLTO RUIZ, MARIA DOLORES |
(9635) 43400 |
|||
MOYA SIMARRO, ANDRES |
Integrative Systems Biology Institute (I2Sysbio); University of València and Spanish Research Council (CSIC); c/ Catedrático José Beltrán 2, 46980 Paterna, València, Spain. Foundation for the Promotion of Sanitary and Biomedical Research of Valencian Community (FISABIO); Avenida de Cataluña 21, 42... (9635) 43480 |
Biography | ||
I studied simultaneously Biology and Philosophy at the Universitat de València (UV), obtaining a Ph.D. in Biology in 1983, and a Ph.D. in Philosophy in 1988. I was a Postdoctoral Fellow at the University of California, Davis (USA), in 1985-1986, and I have been invited Prof. in the University of California, Irvine (USA), in 1988 and 1994. After coming back from my post doctorate in the USA, in 1986, I created the Evolutionary Genetics Research Group at the Department of Genetics of the UV, where I am Prof. of Genetics since 1993, and have been its Director from 1995 to 1998. I was the promoter of the Cavanilles Institute of Biodiversity and Evolutionary Biology at the UV. I also promoted the creation of the Astrobiology Centre (CSIC-INTA), the Public Health Research Centre (CSISP), now integrated into the Valencian Region Foundation for the Promotion of Health (FISABIO) and the Integrative Systems Biology Centre (UV and Spanish Research Council, CSIC). Currently, I chair the Institutional Professorship FISABIO-UV. I am author of about six hundred publications about Genetics, Evolution and Philosophy of Biology. My most significant contributions are in the fields of Symbiosis and Bacterial Genomics. I am involved in the study of the Human and Animal Microbiomes under an Evolutionary and Systems Biology perspective. I am founder member of the European Society for Evolutionary Biology, the Spanish Society of Virology and the Spanish Society of Evolutionary Biology, from which I was president between 2009-2017. I received the "Ciutat de Barcelona Award for Scientific Research" (1996), "Diario Médico Award" (2006), "Diploma of the President of the Valencian Government for excellence in Biomedical Research" (2010), "National Genetics Award" (2012), "Lilly Foundation Biomedical Research Award" (2013), "Mexico Award in Science and Technology" (2015), "Doctor Honoris Causa by Menendez Pelayo International University" (UIMP, Santander, 2016). I am a fellow of the American Association for the Advancement of Science since 1998. |
||||
OLTRA SOLER, JUAN SILVESTRE |
||||
PARICIO ORTIZ, NURIA |
(9635) 43005 |
|||
PASCUAL CALAFORRA, LUIS FCO. Secretari/a de Departament |
Departament de Genètica despatx nº 34 6è pis, edifici B Campus Burjassot-Paterna (9635) 44504 |
|||
PEREZ ALONSO, MANUEL |
Departamento de Genética Facultad de Biología (Bloque B, 6º piso) Campus de Burjasot (9635) 43179 |
|||
RAUSELL SEGARRA, CAROLINA |
(9635) 43397 |
|||
REAL GARCIA, MARIA DOLORES |
(9635) 43397 |
|||
SANJUAN VERDEGUER, RAFAEL Director/a Titulacio Master Oficial |
(9635) 43270 |
|||
SILVA MORENO, FRANCISCO J. |
(9635) 43650 |