Contracts and Projects financed by the State (last 10 years)

1. Development of new “multitarget” modulators of nuclear receptors and lipid biomarkers for the treatment of metabolic syndrome and associated comorbidities (PI21/02045).
Implementation entity: INCLIVA Health Research Institute
Convening/financing entity: Carlos III Health Institute. Ministry of Science, Innovation and Universities

2. Design, synthesis and pharmacological study of new drugs useful for the treatment of metabolic syndrome (AICO/2021/081)
Implementation entity: University of Valencia
Principal investigator names: Diego M Cortes Martínez
Funding entity(ies): Conselleria d’Innovació, Universitats, Ciència i Societat Digital. Generalitat Valenciana (GVA)

3. Advice on the development of research work to carry out the identification and quantification of phytochemical substances (terpenes, polyphenols, thiols, others) and other bioactive substances such as alkaloids, in the leaves of Sacha Inchi (Pluketia volubilis L.) 2021
Implementation entity: University of Valencia
Principal investigator name: Diego M Cortes Martínez
Financing entity(ies): Association promoting the development of Sacha Inchi-Pro Sacha Inchi

4. Chemical and pharmacological development of new "multitarget" drugs in the treatment of type 2 diabetes mellitus and associated cardiovascular disease (PI18/01450).
Implementation entity: INCLIVA Health Research Institute
Convening/financing entity: Carlos III Health Institute. Ministry of Science and Innovation and Universities

5. Hiring of support personnel linked to the transfer project (APOTIP/2020/011).
Implementation entity: INCLIVA Health Research Institute
Convening/financing entity: Conselleria d’Innovació, Universitats, Ciència i Societat Digital. Generalitat Valenciana (GVA)

6. Advice on the identification and subsequent quantification of alkaloids in the raw and toasted seeds of Sacha Inchi -Pluketia volubilis L.- in case these were detected
Implementation entity: University of Valencia
Principal investigator name: Diego M Cortes Martínez
Financing entity(ies): Association promoting the development of Sacha Inchi-Pro Sacha Inchi
Start-end date: 06/24/2020 - 09/24/2020 (3 months)

7. Synthesis and pharmacological evaluation of new dual PPAR alpha/gamma agonists as new therapeutic tools in the control of cardiometabolic disorders (CP15/00150).
Implementation entity: INCLIVA Health Research Institute
Convening/financing entity: Carlos III Health Institute. Ministry of Science and Innovation

Patents

1. Prenylated benzopyrans PPAR agonists
Inventors/authors/breeders: Cortes D, Sanz MJ, Cabedo N, Bermejo A, Piqueras L, Collado A, Gomes P, Vila L
Rights holder entity: University of Valencia-INCLIVA
Application No.: P201731470 (ES2718000B2, EP3733658B1, WO2019129909A1)
Country of registration: Spain, Valencian Community
Grant date: 12/13/2019 Patent number: PCT/ES2018/070826

2. New isoquinoline derivatives, preparation method and pharmaceutical compositions containing them.
Inventors/authors/breeders: Cortes D, Cabedo N, Andreu I, Bermejo A, Atassi G, Pierre A, Caignard DH, Renard P
Rights holder entity: SERVIER Laboratories
Application No.: P200000185, FR0100245W (WO2001055117A1, ES2172376B1)
Country of registration: France
Registration date: 01/28/2000

3. Phenanthrene derivatives for use as Medications
I. García, A. López, M. C. Álvarez, J. R. Tormo, M. Pérez and D. Cortes
  Application No.: EP12197087.5 Priority Date: December 13, 2012
Owner entity: University of Valencia and Valentia Biopharma
Company that is exploiting it: Valentia Biopharma