Radiopharmacy and drugs stability - R.F.E.M.

Reference of the Group:

GIUV2013-079

 
Description of research activity:

Radiopharmaceuticals for therapeutic and diagnostic use: study of drug labelling conditions and stability of the complexes formed. Radioimmunoanalytical techniques: obtaining a kinetic model for some reactions used in the assessment of different hormones, antigenic substances or antibodies, used in human clinical practice, by developing speed equations for the overall process. establishing the possible reaction mechanism. Study of the influence of different variables such as temperature, viscosity, dielectric constant or ionic strength of the medium. Application of topological methods to the design of new structures with pharmacological activity, using artificial neural networks as methods of discrimination and prediction of properties, allowing the best candidates to be selected for subsequent in vitro experimental trials.

 
Web:
 
Scientific-technical goals:
  • Seleccion de nuevas estructuras con posible actividad farmacologica empleando metodos de conectividad molecular
 
Research lines:
  • Selection of new structures with antifungal activity.Application of topological methods and artificial neural networks to the selection of new structures with antifungal activity and subsequent in vitro analysis against different pathogenic strains.
 
Group members:
Name Nature of participation Entity Description
FACUNDO PEREZ GIMENEZDirectorUniversitat de València
 
CNAE:
  • -
 
Associated structure:
  • Physical Chemistry
 
Keywords:
  • Topologia molecular-Redes neuronales artificiales-Antifungicos