GIUV2016-337
Infertility, or the inability to conceive a child, is a medical condition recognised by the World Health Organisation (WHO) that causes serious health problems for the women affected, as well as significant epidemiological and sociological repercussions for society. It is estimated that this pathology affects 15% of couples worldwide, and its incidence is on the rise. The aim of our activity is to promote and initiate new lines of research that allow us to advance in the knowledge of reproductive medicine, improving assisted reproduction treatments, increasing their success rates and establishing new techniques for the preservation of male fertility.
- Use of Oxidative stress as a biomarker for embryo viability in human IVF
- Artificial gamete creation through germ line reprogramming from human somatic cells
- Male infertility.Our study must be considered an initial attempt to create an in vitro model for the direct conversion of somatic cells from patients with gamete-alterations production into germ cells in vitro, opening the field to discover new cell therapies to treat them in the future.
- Embryo viability.Use of oxidative stress as a biomarker for embryo viability in human IVF and its use as an additional marker to the existing morphokinetic algorithms provided by time-lapse.
| Name | Nature of participation | Entity | Description |
|---|---|---|---|
| JOSE ALEJANDRO REMOHI GIMENEZ | Director | Universitat de València | |
| Research team | |||
| MARCOS MESEGUER ESCRIVA | Collaborator | Clínica IVI | researcher |
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- Valencian Infertility Institute (IVI)
- gamete, somatic cells, reprogramming
- embryo viability, biomarker, IVF, time-laps
