Group of Experimental Gastroenterology - Gastro

Reference of the Group:

GIUV2017-350

 
Description of research activity:

Study of the Physiopathology of acute pancreatitis. Study of the Physiopathology of liver cirrhosis. Study of the cell cycle in hepatocytes.

 
Web:

No Determinada

 
Scientific-technical goals:
  • Estudiar del papel de la regulacion redox en la cascada inflamatoria de la pancreatitis aguda
  • Estudiar el papel de los nucleosomas extracelulares en la respuesta inflamatoria de la pancreatitis aguda
  • Estudiar el papel de la MAP quinasa p38alpha en la regulacion de la defensa antioxidante en higado
 
Research lines:
  • Pathophysiology of acute pancreatitis.Redox signalling in the inflammatory cascade of acute pancreatitis. Role of extracellular nucleosomes in the inflammatory response of acute pancreatitis.
  • Regulation of antioxidant defence.Role of p38 alpha MAP kinase in the regulation of antioxidant defence in hepatocytes.
  • Cell cycle regulation.Role of p38 alpha MAP kinase in the regulation of cytokinesis in hepatocytes.
 
Group members:
Name Nature of participation Entity Description
JUAN JOSE SASTRE BELLOCHDirectorUniversitat de València
Research team
SALVADOR PEREZ GARRIDOMemberUniversitat de València
SERGIO RIUS PEREZMemberUniversitat de València
RAQUEL TALENS VISCONTICollaboratorUniversitat de València
MARIA ISABEL TORRES CUEVASCollaboratorUniversitat de València
 
CNAE:
  • -
 
Associated structure:
  • Physiology
 
Keywords:
  • cytokines, oxidative stress, phosphatases, chromatin remodelling
  • antioxidant enzymes, p38, MAPK
  • cell cycle, mitosis, cytokinesis