GIUV2017-398
The prevalence of frailty syndrome and cognitive impairment represent an often overlapping clinical entity that has a major health, social and economic impact. Frailty and cognitive impairment have also been shown in several international studies to be a precursor to disability, dependency and premature mortality. The group¿s research activity focuses on two fundamental aspects of ageing 1) The pathophysiological alterations that induce and accompany frailty syndrome and cognitive impairment in older people or in younger people whose pathologies and comorbidities lead to earlier development of frailty syndrome and cognitive impairment (such as people with psychiatric illnesses or oncology patients).
2) Nursing multidisciplinary interventions that are able to delay the onset or slow the progression of frailty and cognitive decline. The first aspect is approaches from a clinical perspective by looking for biomarkers in blood, saliva or other biological samples that characterise the frailty syndrome and cognitive impairment or are predictive of its appearance and changes either in the sense of progression or improvement after clinical interventions. The use of a panel of biomarkers...The prevalence of frailty syndrome and cognitive impairment represent an often overlapping clinical entity that has a major health, social and economic impact. Frailty and cognitive impairment have also been shown in several international studies to be a precursor to disability, dependency and premature mortality. The group¿s research activity focuses on two fundamental aspects of ageing 1) The pathophysiological alterations that induce and accompany frailty syndrome and cognitive impairment in older people or in younger people whose pathologies and comorbidities lead to earlier development of frailty syndrome and cognitive impairment (such as people with psychiatric illnesses or oncology patients).
2) Nursing multidisciplinary interventions that are able to delay the onset or slow the progression of frailty and cognitive decline. The first aspect is approaches from a clinical perspective by looking for biomarkers in blood, saliva or other biological samples that characterise the frailty syndrome and cognitive impairment or are predictive of its appearance and changes either in the sense of progression or improvement after clinical interventions. The use of a panel of biomarkers that can be measured in routine clinical testing allows the detection of individuals at risk of developing frailty and cognitive decline or progressing to more severe stages of frailty and dependence, monitoring the effectiveness of treatments, non-pharmacological interventions and care that slow or delay frailty and cognitive decline or its progression. In the aspect of clinical interventions, the impact that these have on other fundamental variables in the integral assessment of the patient is also evaluated, such as their functional state, mode and quality of life from a holistic perspective of people.
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- Estudio de las bases fisiopatologicas del sindrome de fragilidad: evaluacion de marcadores y determinacion de su valor pronostico.
- Determinar el sindrome de fragilidad en personas mayores con diversas patologias cronicas y conocer su impacto en terminos de capacidades funcionales, salud mental y calidad de vida.
- Evaluar el impacto de la nutricion, de la actividad fisica y ocupacional y del genero en el tratamiento de la fragilidad y deterioro cognitivo.
- Diseñar intervenciones enfermeras y multidisciplinares para prevenir o retrasar la aparicion del sindrome de fragilidad y del deterioro cognitivo.
- Frailty.Research on frailty sydnrome, a syndrome that appears as a response to different stressful situations and that can serve as a conceptual and experimental framework to explain some of the different pathways that lead to disability and dependence in elderly or vulnerable patients. Study of effective interventions to prevent or delay the progression of the frailty syndrome.
- Cognitive impairment.Characterisation of cognitive impairment, its relationship with the frailty syndrome and searches for diagnostic and prognostic biomarkers. Study of effective interventions to prevent or delay the progression of cognitive impairment in vulnerable people.
| Name | Nature of participation | Entity | Description |
|---|---|---|---|
| OMAR CAULI | Director | Universitat de València | |
| Research team | |||
| JULIO JORGE FERNANDEZ GARRIDO | Member | Universitat de València | |
| VANESSA SANCHEZ MARTINEZ | Member | Universitat de València | |
| ANNA NATURA COLOMER PEREZ | Member | Universitat de València | |
| ANNA NATURA COLOMER PEREZ | Member | CEIP FP Ciutat de l'Aprenent | professor |
| SILVIA CORCHON ARRECHE | Member | Universitat de València | |
| RUT NAVARRO MARTINEZ | Member | Universitat de València | |
| CRISTINA BUIGUES GONZALEZ | Member | Universitat de València | |
| ROSA MARIA FONFRIA VIVAS | Member | Universitat de València | |
| FRANCISCO MIGUEL MARTINEZ ARNAU | Member | Universitat de València | |
| OSCAR CABALLERO LUNA | Member | Universitat de València | |
| CONCEPCION MARTINEZ MARTINEZ | Member | Universitat de València | |
| MARIA PILAR PEREZ ROS | Member | Universitat de València | |
| MARIA VANESSA IBAÑEZ DEL VALLE | Member | Universitat de València | |
| LUCIA ORTEGA PEREZ DE VILLAR | Member | Universitat de València | |
| MARIA LUISA BALLESTAR TARIN | Collaborator | Universitat de València | |
| IVAN JULIAN ROCHINA | Collaborator | Universitat de València | |
| EMMANUEL MARIA NAVARRO FLORES | Collaborator | Universitat de València | |
| CARMEN GARCIA GOMARIZ | Collaborator | Universitat de València | |
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- Nursing
- geriatria; valoracion integral; gerontologia; cuidados
- cognicción;depresión;calidad de vida
