Synthesis, reactivity and coordination chemistry of heterocyclic compounds, pharmacological activity - GHC

Reference of the Group:

GIUV2017-392

 
Description of research activity:

Synthesis of heterocyclic nitrogen compounds and subsequent study of their chemical reactivity. Study the ability of the prepared compounds to coordinate with different cationic and/or anionic species and study the possible applications of these interactions. Based on this knowledge, the possible pharmacological activity of the prepared compounds will be studied.

 
Web:

http://www.uv.es/uvweb/departamento-quimica-organica/es/investigacion/lineas-investigacion/sintesis-reactividad-quimica-coord

 
Scientific-technical goals:
  • Development of new synthetic methodologies for the preparation of nitrogenous heterocyclic compounds.
  • Study of the reactivity of the prepared compounds: Acid-base properties, reactivity towards nucleophiles and electrophiles. Functionalization reactions.
  • Interaction studies of the prepared heterocycles with cationic and/or anionic species as well as with biomolecules. Applications as sensors.
  • Study of the possible pharmacological activity of the prepared compounds.
 
Research lines:
  • Heterocyclic chemistry.Synthesis of heterocyclic nitorgen compounds and subsequent study of their chemical reactivity. Study of the capacity of the compounds prepared to coordinate with different cationic and/or anionic species and study the possible applications of these interactions. Based on this knowledge, the possible pharmacological activity of the compounds prepared will be studied.
 
Group members:
Name Nature of participation Entity Description
RAFAEL BALLESTEROS CAMPOSDirectorUniversitat de València
Research team
BELEN ABARCA GONZALEZMemberUniversitat de València - Estudi GeneralUVEG honorary professor
 
CNAE:
  • -
 
Associated structure:
  • Organic Chemistry
 
Keywords:
  • NITROGENOUS HETEROCYCLES
  • SUPRAMOLECULAR CHEMISTRY