GIUV2025-654
Liquid Biopsy in Oncology for Optimization and Precision in Solid Tumors is a research group focused on the development, validation, and implementation of innovative technologies in the field of liquid biopsy, aiming to optimize the clinical management of patients with solid tumors. The group's work is oriented towards improving diagnosis, risk stratification, disease monitoring, and treatment selection through the analysis of circulating tumor-derived components in biological fluids, primarily blood.
The group is part of the eOM Group: Excellence in Molecular Oncology (https://oncologiamolecularvalencia.com), a translational research initiative composed of a highly qualified, multidisciplinary team. It brings together experts in molecular biology, medical oncology, bioinformatics, genomics, biotechnology, and related fields, enabling a comprehensive and cuttingedge approach to cancer research.
BLOOP's main research efforts are focused on the identification, characterization, and clinical validation of novel tumor biomarkers ¿ diagnostic, prognostic, and predictive ¿ through liquid biopsy technologies, including circulating tumor DNA (ctDNA), cell-free RNA, circulating tumor...Liquid Biopsy in Oncology for Optimization and Precision in Solid Tumors is a research group focused on the development, validation, and implementation of innovative technologies in the field of liquid biopsy, aiming to optimize the clinical management of patients with solid tumors. The group's work is oriented towards improving diagnosis, risk stratification, disease monitoring, and treatment selection through the analysis of circulating tumor-derived components in biological fluids, primarily blood.
The group is part of the eOM Group: Excellence in Molecular Oncology (https://oncologiamolecularvalencia.com), a translational research initiative composed of a highly qualified, multidisciplinary team. It brings together experts in molecular biology, medical oncology, bioinformatics, genomics, biotechnology, and related fields, enabling a comprehensive and cuttingedge approach to cancer research.
BLOOP's main research efforts are focused on the identification, characterization, and clinical validation of novel tumor biomarkers ¿ diagnostic, prognostic, and predictive ¿ through liquid biopsy technologies, including circulating tumor DNA (ctDNA), cell-free RNA, circulating tumor cells (CTCs), extracellular vesicles, and other circulating components. These tools are essential for the advancement of Precision Oncology, enabling treatment to be tailored to the molecular characteristics of each patient and allowing real-time, minimally invasive tumor monitoring.
Ultimately, the BLOOP group plays an active role in translating scientific knowledge into clinical practice, with the overarching goal of improving the prognosis and quality of life of cancer patients through a more personalized, effective, and molecularly informed approach to medicine.
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- Impacto Clinico: Reducir la necesidad de biopsias tisulares invasivas o complementar los estudios moleculares mediante el uso de biopsia liquida
- Colaboracion Interdisciplinaria: Fomentar alianzas con instituciones academicas, hospitales y empresas biotecnologicas para acelerar la traslacion
- Capacitacion: Formar a nuevos investigadores en tecnicas de biopsia liquida y analisis molecular avanzado
- Innovacion Tecnologica: Diseñar sistemas altamente sensibles y especificos para la deteccion de biomarcadores
- Development of advanced diagnostic tools.Explore highly sensitive and specific systems for biomarker detection. Develop technologies for more accessible diagnostics in clinical settings. Incorporate artificial intelligence for advanced analysis of data derived from liquid biopsies.
- Personalized medicine and targeted therapies.Integration of molecular data obtained from liquid biopsies into tumour progression to design the best strategy. Implement pilot liquid biopsy programmes to assess their feasibility and clinical applicability. Optimise early detection protocols in high-risk patients.
- Identification and validation of new biomarkers.BLOOP promotes the transfer and application of findings from liquid biopsy biomarkers in basic research for clinical validation. Participate in national and international research networks to share data and innovative strategies.
| Name | Nature of participation | Entity | Description |
|---|---|---|---|
| SILVIA CALABUIG FARIÑAS | Director | Universitat de València | |
| Research team | |||
| LIRIA TERRADEZ MAS | Member | Universitat de València | |
| VEGA IRANZO GONZALEZ-CRUZ | Member | Universitat de València | |
| NURIA SANTONJA LOPEZ | Member | Universitat de València | |
| MARIA ESTHER ROSELLO SASTRE | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | head of section/service |
| DANIEL MONLEON SALVADO | Collaborator | Universitat de València | |
| LARA NAVARRO CERVERO | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | technical officer |
| EVA SERNA GARCIA | Collaborator | Universitat de València | |
| JOSE MANUEL MORALES TATAY | Collaborator | Universitat de València | |
| FRANCISCO JAVIER MEGIAS VERICAT | Collaborator | Universitat de València | |
| TERESA CONSUELO SAN MIGUEL DIEZ | Collaborator | Universitat de València | |
| MARIA JOSÉ SAFONT AGUILERA | Collaborator | Universitat de València | |
| MARIA JOSÉ SAFONT AGUILERA | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | doctor |
| EVA ESCORIHUELA ALARES | Collaborator | FUNDACIO INVESTIGACIO HOSPITAL GENERAL UNIVERSITARI VALENCIA | research support technician |
| SANDRA GALLACH GARCIA | Collaborator | FUNDACIO INVESTIGACIO HOSPITAL GENERAL UNIVERSITARI VALENCIA | researcher |
| MIREIA GIL RAGA | Collaborator | Hospital de Requena | doctor |
| ELOISA JANTUS LEWINTRE | Collaborator | FUNDACIO INVESTIGACIO HOSPITAL GENERAL UNIVERSITARI VALENCIA | researcher |
| MARAIS MOSQUEDA FROMETA | Collaborator | FUNDACIO INVESTIGACIO HOSPITAL GENERAL UNIVERSITARI VALENCIA | research support technician |
| ALBERTO JACOBO CUNQUERO TOMÁS | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | pre-tenured lecturer |
| PAULA ESPINOSA OLARTE | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | pre-tenured lecturer |
| MARTÍN NUÑEZ ABAD | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | pre-tenured lecturer |
| ESTER MUNERA MARAVILLA | Collaborator | Centro de Investigación Biomédica en Red en Cancer | postdoctoral researcher |
| AMAYA FERNANDEZ DÍAZ | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | pre-tenured lecturer |
| MIRIAM LOBO DE MENA | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | pre-tenured lecturer |
| JOSÉ ÁNGEL GARCÍA | Collaborator | CONSORCIO HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA | technical officer |
| SUSANA TORRES MARTÍNEZ | Collaborator | FUNDACIO INVESTIGACIO HOSPITAL GENERAL UNIVERSITARI VALENCIA | postdoctoral researcher |
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- Pathology
