GIUV2025-665
The objective of the Research Group on Environmental Risk Assessment of Xenobiotics is the study of synthetic substances (biocides, pesticides, drugs, nanoparticles, etc.) with (eco)toxicological effects on ecosystems as a whole and individually on the organisms that inhabit them.
In recent years, the study of the effects of substances considered emerging or priority substances and of a new typology of compounds whose properties are not comparable to those of traditional substances, namely nanoparticles, has been of great interest.
In this sense, GERAX approaches in an integral way the study of these substances in the environment evaluating the effects on the trophic chains and on the organisms individually in different environments (soils, continental and marine waters, sediments), applying standardized ecotoxicological bioassays (ISO and OECD), batteries of
multi-trophic and microcosm bioassays; for this purpose it applies and develops (eco)toxicity bioassays based on the use of indicator organisms. Environmental risk assessment is performed in an integrated manner, understanding ecosystems as a set of complex but interrelated compartments. The group is an expert in the...The objective of the Research Group on Environmental Risk Assessment of Xenobiotics is the study of synthetic substances (biocides, pesticides, drugs, nanoparticles, etc.) with (eco)toxicological effects on ecosystems as a whole and individually on the organisms that inhabit them.
In recent years, the study of the effects of substances considered emerging or priority substances and of a new typology of compounds whose properties are not comparable to those of traditional substances, namely nanoparticles, has been of great interest.
In this sense, GERAX approaches in an integral way the study of these substances in the environment evaluating the effects on the trophic chains and on the organisms individually in different environments (soils, continental and marine waters, sediments), applying standardized ecotoxicological bioassays (ISO and OECD), batteries of
multi-trophic and microcosm bioassays; for this purpose it applies and develops (eco)toxicity bioassays based on the use of indicator organisms. Environmental risk assessment is performed in an integrated manner, understanding ecosystems as a set of complex but interrelated compartments. The group is an expert in the assessment of soils contaminated by anthropogenic activities, especially industrial and mining activities, but also by the use of agrochemicals.
The growing demand by the EU for the generation of alternative systems to animal experimentation has allowed GERAX to establish collaborations with other research groups and companies that develop computational models designed to predict the (eco)toxicological effect of chemical substances on a multitude of biological targets, in this sense, GERAX participates in the experimental validation of these models designed in silico.
The monitoring of environmental pollutants and the study of the impacts on living beings is another important field of study for GERAX, where the experience in the study of mutagenicity, genotoxicity and cytotoxicity in in vivo and in vitro models has allowed to establish the health and environmental risk of these new generation substances.
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- Evaluar el Riesgo Ambiental de nueva sustancias quimicas con efectos perjudiciales para el medio ambiente desde un punto de vista integrado
- Environmental Risk Assessment (ERA).Assessment of the impact of xenobiotics: biocides, pesticides, PFAS, pharmaceuticals, nanoparticles, nanoplastics and emerging pollutants in environmental matrices in accordance with European directives (REACH, BPR, CLP).
- Environmental monitoring.Design and application of multitrophic batteries for monitoring toxicity in terrestrial and aquatic ecosystems, both continental and marine.
- Computational (eco)toxicology.Experimental validation of models for predicting (eco)toxicological properties based on QSAR systems.
- Environmental exposure assessment.Study of the toxic effect of exposure to xenobiotics on living beings (biomarkers, oxidative stress, mutagenicity, cytotoxicity and genotoxicity).
| Name | Nature of participation | Entity | Description |
|---|---|---|---|
| OSCAR ENRIQUE ANDREU SANCHEZ | Director | Universitat de València | |
| Research team | |||
| JESUS VICENTE DE JULIAN ORTIZ | Collaborator | Universitat de València | |
| JESUS MUÑOZ BERTOMEU | Collaborator | Universitat de València | |
| EUGENIO GOMEZ MINGUET | Collaborator | Universitat de València | |
| EULALIA MARÍA BELTRÁN RODRÍGUEZ | Collaborator | Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria - CSIC | tenured scientist |
| BORJA MERCADO CASARES | Collaborator | UNIVERSIDAD EUROPEA DE VALENCIA | professor |
| Mª VICTORIA PABLOS CHI | Collaborator | Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria - CSIC | tenured scientist |
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- Plant Biology
