Supramolecular Chemistry - SUPRAMOL

Reference of the Group:

GIUV2013-107

 
Description of research activity:

The Supramolecular Chemistry group focuses its research work on the synthesis and characterisation of polynitrogen compounds, as well as on the study of their interaction with metal ions, anions and neutral species. Special attention is dedicated to the study of systems of environmental and/or biological interest. In particular, to the development of molecules and/or complexes with antioxidant and/or anti-inflammatory, antiparasitic and/or antitumour activity. In order to prepare more efficient systems, the implementation of molecules on different solid surfaces such as nanoparticles, mesoporous solids, etc. is studied. These systems are applied to the detection of compounds of environmental interest and the development of new types of drugs. Finally, new compounds for nuclear magnetic resonance imaging are prepared and studied.

 
Web:
 
Scientific-technical goals:
  • Desarrollo de compuestos con actividad antioxidante, antiparasitaria y antitumoral. Deteccion y reconversion de compuestos con interes medioambiental
 
Research lines:
  • Biomimetic chemistry of copper. Application to NMR.Study of biomimetic compounds and copper enzymes by paramagnetic NMR.
  • Anion recognition.Development and synthesis of compounds capable of recognising anions of biological and/or environmental interest.
  • Enzyme mimics.To develop different compounds or families of compounds whose purpose is the mimicry of enzymatic active centres.
  • Modification of solid surfaces.Development of oxide nanoparticles and their functionalisation with different receptors for catalysis, pharmacological application.
  • Synthesis of polyamides.To synthesise different families of polyamine/polyamide compounds by new or already established synthetic routes for the development of the different lines of research.
  • Contrast agents.Development of new compounds capable of acting as contrast agents in biomedicine.
 
Group members:
Name Nature of participation Entity Description
ENRIQUE GARCIA-ESPAÑA MONSONISDirectorUniversitat de València
Research team
HERMAS RAFAEL JIMENEZ GARCIAMemberUniversitat de València
JOSÉ MIGUEL LLINARES BERENGUERMemberUniversitat de València
BEGOÑA VERDEJO VIUMemberUniversitat de València
MARIA TERESA ALBELDA GIMENOMemberUniversitat de València
JUAN CARLOS FRIAS MARTINEZCollaboratorUniversidad CEU Cardenal Herreraprofessor
M DESAMPARADOS SORIANO SOTOCollaboratorUniversitat Politècnica de Valènciaprofessor
 
CNAE:
  • -
 
Associated structure:
  • Institute of Molecular Science (ICMOL)
 
Keywords:
  • Cobre, RMN paramagnético, compuestos biomiméticos
  • Macrociclos, azoles, aniones, detección, dioxido de carbono
  • Enzimas, Complejos, catálisis, miméticos
  • nanopartículas,alumina,sílice,mesoporosos
  • Poliaminas,poliamidas,aniones,reconocimiento,actividad biológica.
  • gadolinio, RMI, macrocuclos,lisosomas,agentes teranósticos.