Grups d'Investigació

GIUV2016-281

Women present a specific profile in many areas of ageing, including frailty, chronic diseases (examples are clearly musculoskeletal diseases, cardiovascular diseases, certain forms of cancer, cognitive impairment or depression), social interaction, and quality of life. Our activity has focused on the female determinants of osteoporosis and cardiovascular diseases, quality of life after menopause, cognitive impairment and, more recently, frailty. More recently, we have also been doing research on endometriosis, a disease that causes morbidity and affects quality of life, and whose impact on healthy ageing is just beginning to be understood. We have carried out basic and applied research work, and are therefore an example of a multidisciplinary group with interaction between basic and clinical researchers and with a profile of publications and funded projects that meet this criterion.

http://www.salusvitae.es www.saludmujerclinico.es

• Envejecimiento saludable en la mujer
• Osteoporosis
• Senescencia reproductiva
• Endometriosis
• Fragilidad y Deterioro cognitivo

• Genetics of osteoporosis and bone fractures.The objectives of this line of research are, on the one hand, to identify genes and polymorphisms associated with bone phenotypes through candidate gene association studies and through translational studies from animal models, and on the other hand, the functional characterisation of each variant.
• Long-term effects of maternal and oocyte aging on offspring; Assisted reproduction and infertility; Female reproductive physiology and endocrinolo.The objectives of these lines of research are to clarify at epidemiological/population, cellular and molecular/epigenetic levels the effect of maternal oocyte ageing and the assisted reproduction techniques on the reproductive health of women and their offspring.
• Prevention of chronic disease in women.Women have a specific disease profile, which is particularly evident in some pathologies, such as osteoporosis, heart disease, etc. It is important to develop prevention policies, especially through healthy lifestyles, including physical activity, and with the support of ICTs.
• Frailty in women.Frailty is a state of vulnerability to illness and death and in its early stages can be prevented. It is more prevalent in women than in men in every age group. Multidimensional frailty, both physically and cognitively, its prevalence and characteristics are investigated.
• Psico-social frailty.The psychological aspect of frailty includes clinical (cognitive and emotional), functional and socio-familial aspects as well as different demographic and lifestyle variables. The aim is to research and define the profile of these variables in different population groups.

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• Pediatrics, Obstetrics and Gynaecology

• Biología de la reproducción, 218960 - Efectos a largo plazo sobre la descendencia; Envejecimiento reproductivo; Reproducció
• Mujer, osteoporosis, enfermedad cardiovascular, menopausia, actividad física, nutrición, cumplimiento, TIC (tecnologías de información y comunicación)
• Fragilidad, mujer, cognición, calidad de vida, estado de ánimo, depresión.
• Fragilidad, envejecimiento óptimo, psicopatología, evaluación multidisciplinar
• Osteoporosis, osteoinmunología, SNPs, genética funcional, estudios de asociación