GIUV2025-676
Our research group focuses on the detailed and multidisciplinary analysis of periodontal and peri-implant diseases, as well as their connection to systemic pathologies. These diseases represent a significant challenge both clinically and in research due to their high prevalence, functional and aesthetic impact, and potential association with various systemic conditions. We are dedicated to understanding the etiological, pathophysiological, and therapeutic processes of these diseases, approaching them from a comprehensive perspective that combines basic and applied research. In this context, we evaluate alterations affecting the periodontium and dental implants, from their onset to advanced stages, considering both intrinsic host factors and external triggers. This approach enables us not only to enhance scientific knowledge in the field but also to develop innovative strategies to optimize clinical outcomes, positively impacting patients' oral and general health.
Furthermore, our work aims to address current challenges in managing these conditions, which require personalized, evidence-based approaches. Our research pays special attention to factors influencing the onset and...Our research group focuses on the detailed and multidisciplinary analysis of periodontal and peri-implant diseases, as well as their connection to systemic pathologies. These diseases represent a significant challenge both clinically and in research due to their high prevalence, functional and aesthetic impact, and potential association with various systemic conditions. We are dedicated to understanding the etiological, pathophysiological, and therapeutic processes of these diseases, approaching them from a comprehensive perspective that combines basic and applied research. In this context, we evaluate alterations affecting the periodontium and dental implants, from their onset to advanced stages, considering both intrinsic host factors and external triggers. This approach enables us not only to enhance scientific knowledge in the field but also to develop innovative strategies to optimize clinical outcomes, positively impacting patients' oral and general health.
Furthermore, our work aims to address current challenges in managing these conditions, which require personalized, evidence-based approaches. Our research pays special attention to factors influencing the onset and progression of these pathologies. We rigorously analyze biological, genetic, epigenetic, microbiological, and environmental factors, assessing their role in the development of periodontal and peri-implant diseases. These studies include characterizing underlying inflammatory mechanisms, host-microorganism interactions, and the impact of environmental factors such as smoking, stress, and diet. We also explore how individual patient characteristics, such as genetic predisposition or systemic health status, can influence disease progression and responses to various therapeutic interventions. In this way, we seek to optimize current treatment protocols and develop innovative therapies for more efficient and personalized clinical management.
Additionally, our scientific work addresses the interrelation between periodontal and peri-implant diseases and various systemic pathologies. There is growing evidence linking these conditions to chronic diseases such as diabetes, cardiovascular diseases, pregnancy complications, and even certain types of cancer. Our research focuses on identifying and understanding the biological mechanisms that connect these local diseases to systemic processes, such as low-grade chronic inflammation, microbiological dysbiosis, and bacterial translocation. This knowledge is crucial for integrating oral health management into a global medical approach that promotes more comprehensive and effective care.
The ultimate goal of our group is to generate robust scientific knowledge that contributes to advancing the understanding, prevention, diagnosis, and treatment of these diseases. We promote interdisciplinary collaboration at national and international levels, establishing synergies with other research groups, academic institutions, and healthcare professionals. By integrating scientific findings into clinical practice, we aim to improve patients' quality of life, reduce the global burden of these diseases, and contribute to a more holistic view of health that effectively connects oral health with systemic health.
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- Estudiar la etiologia y tratamiento de enfermedades periodontales y periimplantarias, y su relacion con patologias sistemicas para mejorar la salud
- Epigenetics and genetics in periodontal diseases: molecular bases and their etiological and regulatory role..This line of research investigates epigenetics and microRNAs in periodontal diseases, analysing their role in inflammation and tissue destruction. It seeks to identify biomarkers and develop personalised strategies for periodontal diagnosis, prevention and treatment.
- Periodontal Diseases and Their Connection with Cancer.This line of research analyses the connection between periodontal diseases and cancer, exploring biological mechanisms, common risk factors and microbiological interconnections, highlighting the impact of chronic inflammation and the oral microbiome on oncological pathologies.
- Therapeutic Advances in the Treatment of Periodontal and Peri-Implant Diseases.This line seeks to develop and evaluate new treatments for periodontal and peri-implant diseases, including regenerative therapies, microbiome modulation, antimicrobial approaches, and minimally invasive techniques, improving clinical outcomes and quality of life.
- Bibliometrics in the Field of Periodontology.This line analyses scientific output in periodontology using bibliometrics, identifying trends, emerging areas, international collaboration and the impact of publications, in order to guide future studies and strengthen scientific evidence in the field.
| Name | Nature of participation | Entity | Description |
|---|---|---|---|
| ANDRES LOPEZ ROLDAN | Director | Universitat de València | |
| Research team | |||
| FRANCISCO JOSE GIL LOSCOS | Collaborator | Universitat de València | |
| PEDRO JOSE ALMIÑANA PASTOR | Collaborator | Universitat de València | |
| MARTA JORDAN LOPEZ | Collaborator | Universitat de València | |
| ANA RODRIGUEZ MUÑOZ | Collaborator | Universitat de València | |
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- Stomatology
