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Changes with age of the interactions of the microbiota with its human host and deter-mination of a permanent core of mutualistic symbionts
Acronym

MUTUALCORE

Description

Title: Changes with age of the interactions of the microbiota with its human host and determination of a permanent core of mutualistic symbionts

Research groups: Evolutionary Genetics and Theory, Bioinformatics and Computation

In this project we aim to demonstrate: 1) The existence of nucleus of microbial taxa that are true mutualistic symbionts and are present throughout the life of the human host; Specifically, we will determine the universal presence (by geographic distribution and throughout life) of species and genders corresponding to at least seven families of microorganisms that have co-evolved with the human species and we will perform their functional analysis; and 2) the existence of microbial taxa that are responding adaptively to host demands or external factors at specific moments in its life, showing a coupling of these taxa with the host.

Total amount: 290.400 €

Ref: PID2019-105969GB-I00

Ministerio de Ciencia, Innovación y Universidades

Developers of the project
Institut de Biologia Integrativa de Sistemes (I2SYSBIO)
Principal investigators:
  • Moya Simarro, Andres
  • PDI-Catedratic/a d'Universitat
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Non-UV principal researchers

  • Pilar Francino

Participating researchers:
  • Diaz Villanueva, Wladimiro
  • PDI-Titular d'Universitat
View details
Non-UV participating researchers

  • José Castro
  • Alejandro Artacho

Start date
2020 June
End date
2024 December
Funding agencies:

Ministerio de Ciencia e Innovación y Universidades