Grups d'Investigació

GIUV2013-025

The characterisation of drug release, absorption, distribution, metabolism and excretion processes has a major impact on medicine design and provides rational criteria for selecting the most appropriate dosage form, route and method of administration. These aspects are particularly important for drugs with bioavailability problems and/or high pharmacokinetic variability. The research group is dedicated to pre-formulation studies of medicine (and cosmetics), characterisation of drug release and/or absorption processes from the medicine containing them and evaluation of the pharmacokinetic profile after its administration to the organism.

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• Aportar conocimientos que faciliten la obtencion de formas farmaceuticas eficaces y seguras y permitir seleccionar las pautas de administracion

• Preformulation.Galenic development, preferably modified-release oral and topical dosage forms. Evaluation of transdermal administration with iontophoresis.
• Pharmacokinetic evaluation of drugs administered intravenously, orally and tranasdermally.Pharmacokinetic evaluation of drugs administered intravenously, orally and through the skin, especially those with bioavailability problems and/or plasma concentrations with high variability and which correlate poorly with the dose administered.

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• ERI Molecular Recognition and Tech. Development (REMOTE)

• BIOADHESIÓN
• absorción gastrointestinal, penetración transdérmica, dermofarmacocinética, farmacocinética, modelos animales, Gastrointesinal absorption, transderm
• MICROPARTICLES
• LIPOSOMAL VESICLES
• HYDROGELS
• THERAPEUTIC DELIVERY SYSTEMS
• POLYMERIC INSERTS
• RELEASE KINETICS
• TRANSDERMAL PENETRATION
• DERMOPHARMACOKINETICS
• GASTROINTESTINAL ABSORPTION