The UV research groups (GIUV) are regulated in the 1st chapter of the Regulation ACGUV48/2013, which explains the procedure for creating new research structures. They are basic research and organizational structures that result from the voluntary association of researchers that share objectives, facilities, resources and common lines of research. These researchers are also committed to the consolidation and stability of their activity, work in groups and the capability to achieve a sustainable funding.
The research groups included in the previously mentioned Regulation are registered in the Register of Research Structures of the Universitat de València (REIUV), managed by the Office of the Vice-principal for Research. The basic information of these organisms can be found in this website.
Participants
Data related to research groups featured in various information dissemination channels shall not, under any circumstances, imply a statement or commitment regarding the employment or academic affiliation of individuals associated with the Universitat de València. Their inclusion is solely the responsibility of the group directors. Updates will be made upon request from interested parties.
- Registered groups in the Register of Research Structures of the Universitat de València - (REIUV)
Reference of the Group:
Description of research activity: The research group Laboratorio de Investigación en Células Endoteliales (L.In.C.E.) is made up of a multidisciplinary team of researchers with expertise in Vascular and Endocrine Physiology, Molecular Biology, Biochemistry, Cell Biology and Reproductive Biology. The group's main line of research is the study of the vascular effects of oestrogens and other steroid hormones. To this end, a translational approach is used, involving endothelial cells in culture, experiments carried out in animal models and studies carried out in women who receive hormone replacement therapy after menopause. Recently, another line of research on endothelial dysfunction associated with ageing has been initiated. The group's research includes gene and protein expression studies, production of vasoactive substances and functional studies using molecular biology (PCR, RT-PCR, microarrays), biochemistry (western blot, immunofluorescence, ELISA, HPLC), cell biology (primary cultures of human endothelial cells, flow cytometry) and vascular physiology (vascular reactivity).
Web:
Scientific-technical goals: - Diferencias de genero en el area cardiovascular
- Efectos vasculares de las hormonas sexuales
- Identificacion de nuevas rutas de señalizacion reguladas hormonalmente en el endotelio
- Interaccion de las hormonas sexuales con factores proaterogenicos
- Determinacion de celulas endoteliales progenitoras y circulantes y su relacion con el tratamiento hormonal
Research lines: - Analysis of endothelial production of vasoactive compounds.Quantification of the main vasoactive compounds and study of the regulatory pathways involved.
Group members:
Associated structure: 
