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  • Registered groups in the Register of Research Structures of the Universitat de València - (REIUV)

Multivariate and Multicomponent Analysis Group - Quality and high-throughput bioanalysis - GAMM-CyBAR

Reference of the Group:

GIUV2013-111

 
Description of research activity:

Quality and methodology applied to laboratories of routine (ISO 17205 Standard) and research: Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results. Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors. Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.). Added value: In vitro estimation of ecotoxicological parameters. Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value In vitro estimation of ADME/TOX indicators. Development of molecular biointeraction models. Computational simulation methods (¿in silico¿ via ¿Molecular Docking¿). Pharmacophores. QSAR.

 
Web:

http://www.uv.es/sagrado/

 
Scientific-technical goals:
  • Calidad y metrología aplicada a laboratorios
  • Desarrollo de herramientas metodológicas para empresas y laboratorios
  • investigación y desarrollo de métodos (bio)analiticos de alto rendimiento
  • Ensayos químicos de compuestos de interés en muestras medioambientales y de moléculas bioactivas
 
Research lines:
  • Molecular and computational biointeraction.Development of molecular biointeraction models. Computational simulation methods (in silico via Molecular Docking). Pharmacophores. QSAR.
  • Quality and Metrology in Laboratories.ISO 17205 Standard. Development of ad hoc metrological tools, technical protocols, acceptance criteria, validation, quality assurance, control charts, uncertainty, including supporting software. Design of experiments, optimisation, simulation of future results.
  • R&D in (bio)analytical methods.Research and development of high-throughput (bio)analysis methods (Liquid chromatography, Capillary electrophoresis, Mass spectrometry) for the separation and determination of molecules (including chiral) with analytical and bioanalytical applications. (Bio)sensors.
  • Analysis of environmental samples.Chemical assays of relevant compounds in environmental samples (water, sludge, soil, etc.). Added value: In vitro estimation of ecotoxicological parameters.
  • Analysis of bioactive molecules.Chemical assays of bioactive molecules (in urine, plasma, saliva, etc.). Added value in vitro estimation of ADME/TOX indicators.
 
Group members:
Name Nature of participation Entity Description
MARIA JOSE MEDINA HERNANDEZDirectorUniversitat de València
Research team
SALVADOR SAGRADO VIVESMemberUniversitat de València
LAURA ESCUDER GILABERTMemberUniversitat de València
YOLANDA MARTIN BIOSCAMemberUniversitat de València
 
CNAE:
  • -
  • -
  • -
 
Associated structure:
  • Analytical Chemistry
 
Keywords:
  • QSAR
  • ENVIRONMENTAL ANALYSIS
  • ISO 17025 STANDARD
  • CONTAMINATION
  • CONTAMINANT
  • ECOTOXICITY
  • PHARMACOPHORES
  • VALIDITY
  • STATISTICS
  • BIOINFORMATICS
  • ENZYMES
  • MOLECULAR BIOINTERACTION MODELS
  • PROTEINS
  • RECEPTORS
  • MULTIVARIATE ANALYSIS
  • NUMERICAL DATA ANALYSIS
  • QUALITY
  • METROLOGY
  • CHROMATOGRAPHY
  • CAPILLARY ELECTROPHORESIS
  • MASS SPECTROMETRY
  • R&D&I
  • BIOANALYTICAL METHODS
  • CHEMICOANALYTICAL METHODS
  • SEPARATION TECHNIQUES
  • BIOPHARMACEUTICAL ANALYSIS
  • ALTERNATIVE METHODS TO ANIMAL TESTING
  • HIGH-THROUGHPUT METHODS
  • BIOACTIVE MOLECULES
  • MEDICINAL CHEMISTRY