The UV research groups (GIUV) are regulated in the 1st chapter of the Regulation ACGUV48/2013, which explains the procedure for creating new research structures. They are basic research and organizational structures that result from the voluntary association of researchers that share objectives, facilities, resources and common lines of research. These researchers are also committed to the consolidation and stability of their activity, work in groups and the capability to achieve a sustainable funding.
The research groups included in the previously mentioned Regulation are registered in the Register of Research Structures of the Universitat de València (REIUV), managed by the Office of the Vice-principal for Research. The basic information of these organisms can be found in this website.
Participants
Data related to research groups featured in various information dissemination channels shall not, under any circumstances, imply a statement or commitment regarding the employment or academic affiliation of individuals associated with the Universitat de València. Their inclusion is solely the responsibility of the group directors. Updates will be made upon request from interested parties.
- Registered groups in the Register of Research Structures of the Universitat de València - (REIUV)
Reference of the Group:
Description of research activity: The Gastrointestinal Infection Research Group of the Department of Microbiology and Ecology works in the Faculty of Medicine and Dentistry and is linked to the Clinical Microbiology Service of the Hospital Clínico Universitario de Valencia. Our main objective is to investigate the pathogenic mechanisms of infectious agents that produce gastrointestinal pathology, mainly viruses (rotavirus and norovirus), as well as the immune response caused by these infections. Rotavirus and norovirus produce gastroenteritis that affect children, although noroviruses can also infect people of any age, often causing epidemic outbreaks. We study the immunological mechanisms of protection against these infections, as well as the molecular determinants that condition susceptibility to them.
Web:
Scientific-technical goals: - Estudio de los mecanismos patogenicos de rotavirus y norovirus
- Estudio de la respuesta inmunitaria frente a rotavirus y norovirus
- Estudio de las interacciones virus-hospedador
Research lines: - Pathogenesis and immune response to enteric viral infections: rotavirus and norovirus.The aim of this line of research is to study the pathogenic mechanisms and the immune response of infections by the two main enteric viruses (rotavirus and norovirus).
- Molecular epidemiology of rotavirus and norovirus infections.This line of research focuses on the study of the epidemiology of rotavirus and norovirus through the application of molecular techniques (RT-PCR, qPCR, cDNA sequencing, etc.) and the detection of new variants of viral genotypes.
- Study of virus / microbiota / host interactions.The aim of this line of research is to study the interactions that occur between enteric viruses and the host without excluding the interactions that occur between enteric viruses and the intestinal microbiota or the interaction between the intestinal microbiota and the host.
Group members:
CNAE:
Associated structure:
Keywords: - Enterocitos; receptores; antígenos; HBGAs; anticuerpos
- Rotavirus grupo A; genotipos G; genotipos P; norovirus GI; norovirus GII.
- Rotavirus; norovirus; HBGAs; micriobiota; probiótico; receptor
