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  • Registered groups in the Register of Research Structures of the Universitat de València - (REIUV)

Research Group in Biomarkers in Reproduction, Gynaecology and Obstetrics - GIBROG

Reference of the Group:

GIUV2021-523

 
Description of research activity:
The research group is made up of a multidisciplinary team made up of gynecologists, gynecological oncologists, obstetricians, anatomopathologists, biologists, biochemists and chemists who are dedicated to translational research in women's health, including obstetrics, reproduction and benign and oncological gynecological pathologies, with special interest in the search for diagnostic and prognostic biomarkers. The line of research presented here includes the following main research focal points: I) Molecular markers: a) In gynecology and gynecology oncology, in relation to endometriosis, ovarian cancer, ovarian cancer associated with endometriosis, focused mainly on early diagnosis, and the search for prognostic and predictive factors of response to treatment through different omics approaches. b) In reproduction, focused mainly on improving the rate of embryo implantation and the preservation of fertility in oncological patients. c) In obstetric pathologies, with special interest in the prevention of serious pregnancy complications such as preeclampsia and eclampsia. II) Epithelial-mesenchymal transition and immunoregulation: Study of possible interrelationships between the...The research group is made up of a multidisciplinary team made up of gynecologists, gynecological oncologists, obstetricians, anatomopathologists, biologists, biochemists and chemists who are dedicated to translational research in women's health, including obstetrics, reproduction and benign and oncological gynecological pathologies, with special interest in the search for diagnostic and prognostic biomarkers. The line of research presented here includes the following main research focal points: I) Molecular markers: a) In gynecology and gynecology oncology, in relation to endometriosis, ovarian cancer, ovarian cancer associated with endometriosis, focused mainly on early diagnosis, and the search for prognostic and predictive factors of response to treatment through different omics approaches. b) In reproduction, focused mainly on improving the rate of embryo implantation and the preservation of fertility in oncological patients. c) In obstetric pathologies, with special interest in the prevention of serious pregnancy complications such as preeclampsia and eclampsia. II) Epithelial-mesenchymal transition and immunoregulation: Study of possible interrelationships between the mesenchymal-epithelial transition and the presence of immunoregulatory cell populations (Tregs, myelosuppression cells, dendritic cells) and tumor recurrence or progression, with special interest in endometrial cancer, high-grade serous ovarian cancer and ovarian cancer associated with endometriosis.
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Web:

No Determinada

 
Scientific-technical goals:
  • Mejorar el pronostico, diagnostico y calidad de vida de pacientes con patologias relacionadas con la Reproduccion, Ginecologia y Obstetricia
 
Research lines:
  • Line of research in Biomarkers in Reproduction, Gynaecology and Obstetrics.Main areas of research:I) Molecular markers:a) In gynecology and gynecology oncologyb) In reproductionc) In obstetric pathologiesII) Epithelial-mesenchymal transition and immunoregulation
 
Group members:
Name Nature of participation Entity Description
JUAN GILABERT ESTELLESDirectorUniversitat de València
Research team
NURIA SANTONJA LOPEZCollaboratorUniversitat de València
 
CNAE:
  • -
  • -
 
Associated structure:
  • Pediatrics, Obstetrics and Gynaecology
 
Keywords:
  • Reproducción, ginecología, obstetricia, diagnóstico, pronóstico, biomarcadores, endometriosis, ginecología oncológica, medicina traslacional