The UV research groups (GIUV) are regulated in the 1st chapter of the Regulation ACGUV48/2013, which explains the procedure for creating new research structures. They are basic research and organizational structures that result from the voluntary association of researchers that share objectives, facilities, resources and common lines of research. These researchers are also committed to the consolidation and stability of their activity, work in groups and the capability to achieve a sustainable funding.
The research groups included in the previously mentioned Regulation are registered in the Register of Research Structures of the Universitat de València (REIUV), managed by the Office of the Vice-principal for Research. The basic information of these organisms can be found in this website.
Participants
Data related to research groups featured in various information dissemination channels shall not, under any circumstances, imply a statement or commitment regarding the employment or academic affiliation of individuals associated with the Universitat de València. Their inclusion is solely the responsibility of the group directors. Updates will be made upon request from interested parties.
- Registered groups in the Register of Research Structures of the Universitat de València - (REIUV)
Reference of the Group:
Description of research activity: Genetic analysis in solid tumours in children. At European level, we participate in the establishment of a uniform nomenclature, a standard operating procedure and quality validation studies, essential to obtain and maintain a high quality of the results of fluorescent in situ hybridisation, single nucleotide polymorphism and sequencing (FISH, SNPs and NGS) used for therapeutic stratification in neuroblastoma.
Identification of new genetic factors and digital microscopic analysis with prognostic value in low prevalence tumours (rare tumours).
Obtaining and characterising cell lines derived from fresh tumours of neuroblastic and skeletogenic tumours in children.
Establishment and characterisation of in vivo models (2D and 3D) of neuroblastic tumours.
Marker expression studies in paediatric solid tumours and colorectal carcinoma.
Digital pathology studies of the tumour microenvironment.
Web:
Scientific-technical goals: - Estudios de Patologia Digital. Identificacion y validacion de biomarcadores diagnosticos, pronosticos y de seguimiento en muestras histologicas y sangre periferica de pacientes con neoplasias poco prevalentes y en los tumores artificiales relacionados diseñados.
Research lines: - Analysis of genetic prognostic factors in neuroblastoma (NB)..Detection of genomic changes. Identification and characterisation of unusual cases.
- Development of pangenomic techniques of high performance in sarcomas..Use and improvement of tools for genetic diagnosis of tumours.
- Digital microscopy analysis in histopathology.Detection, quantification and objective topology of biological parameters in histological samples.
- Analysis of experimental tumours in animal models.Validation of clinically useful tests.
- Analysis of histopathological prognostic factors in neuroblastoma (NB).Histological category determination and neuroblastic differentiation. Expression studies.
Group members:
| Name |
Nature of participation |
Entity |
Description |
| ROSA NOGUERA SALVA | Director | Universitat de València | |
| Research team |
| SAMUEL NAVARRO FOS | Member | Universitat de València | |
| ANTONIO LLOMBART BOSCH | Collaborator | Universitat de València - Estudi General | UVEG honorary professor |
| ESTHER GAMERO SANDEMETRIO | Collaborator | Consejo Superior de Investigaciones Científicas | trainee research staff |
| ANA PILAR BERBEGALL BELTRAN | Collaborator | Centro de Investigación Biomédica en Red en Cancer | researcher |
| MAITE BLANQUER MACEIRAS | Collaborator | FUNDACION PARA LA INVESTIGACION DEL HOSPITAL CLINICO DE LA COMUNIDAD VALENCIANA (FUNDACION INCLIVA) | trainee research staff |
| NURIA BENAVENT GARCIA | Collaborator | Universitat de València - Estudi General | UVEG PhD student |
| MARIA AMPARO LOPEZ CARRASCO | Collaborator | FUNDACION PARA LA INVESTIGACION DEL HOSPITAL CLINICO DE LA COMUNIDAD VALENCIANA (FUNDACION INCLIVA) | researcher |
| EZEQUIEL MONFERRER GARZARAN | Collaborator | Universitat de València | |
| EZEQUIEL MONFERRER GARZARAN | Collaborator | Universitat de València - Estudi General | UVEG PhD student |
| MERYEM EL OUARDI EL HAMIDY | Collaborator | FUNDACION PARA LA INVESTIGACION DEL HOSPITAL CLINICO DE LA COMUNIDAD VALENCIANA (FUNDACION INCLIVA) | researcher |
| KARINA ALEXANDRA PARRA HARO | Collaborator | Centro de Investigación Biomédica en Red en Cancer | researcher |
| SOFIA GRANADOS APARICI | Collaborator | Centro de Investigación Biomédica en Red en Cancer | researcher |
CNAE:
Associated structure:
Keywords: - Paediatric tumours, neuroblastoma, histopathology, tumour genetics
- Tumores pediátricos, genética tumoral.
- Paediatric tumours, neuroblastoma, tumour genetics.
- Biomedical experimentation in animal models
- Paediatric tumours, neuroblastoma, histopathology
